BACKGROUND: This randomized clinical trial was performed in a single institution to compare the results of minimally invasive video-assisted parathyroidectomy (MIVAP) conducted under regional anaesthesia (RA) or general anaesthesia (GA). METHODS:Fifty-one patients undergoing MIVAP for primary hyperparathyroidism were assigned randomly to either RA (26 patients) or GA (25). RA involved a bilateral deep cervical block, and local infiltration of the incision site with a mixture of 0.25 per cent lignocaine and 0.15 per cent bupivacaine. GA was induced by intravenous administration of propofol, remifentanil and rocuronium bromide. RESULTS: The two groups were matched for age, sex, adenoma size, and preoperative serum calcium and parathyroid hormone levels. The interval from skin incision to closure was similar in the two groups (27.6 and 25.8 min for RA and GA respectively), whereas the total operating time (from induction of anaesthesia to return to the ward) was significantly lower with RA (72.1 versus 90.2 min; P = 0.001). The postoperative requirement for pain medication, measured in terms of amount of ketorolac administered at the request of the patient, was significantly lower in the RA group (28.5 versus 80 mg/day; P < 0.001). CONCLUSION:MIVAP performed under RA was associated with a shorter overall operating time and a reduced need for postoperative pain relief. Copyright2005 British Journal of Surgery Society Ltd.
RCT Entities:
BACKGROUND: This randomized clinical trial was performed in a single institution to compare the results of minimally invasive video-assisted parathyroidectomy (MIVAP) conducted under regional anaesthesia (RA) or general anaesthesia (GA). METHODS: Fifty-one patients undergoing MIVAP for primary hyperparathyroidism were assigned randomly to either RA (26 patients) or GA (25). RA involved a bilateral deep cervical block, and local infiltration of the incision site with a mixture of 0.25 per cent lignocaine and 0.15 per cent bupivacaine. GA was induced by intravenous administration of propofol, remifentanil and rocuronium bromide. RESULTS: The two groups were matched for age, sex, adenoma size, and preoperative serum calcium and parathyroid hormone levels. The interval from skin incision to closure was similar in the two groups (27.6 and 25.8 min for RA and GA respectively), whereas the total operating time (from induction of anaesthesia to return to the ward) was significantly lower with RA (72.1 versus 90.2 min; P = 0.001). The postoperative requirement for pain medication, measured in terms of amount of ketorolac administered at the request of the patient, was significantly lower in the RA group (28.5 versus 80 mg/day; P < 0.001). CONCLUSION:MIVAP performed under RA was associated with a shorter overall operating time and a reduced need for postoperative pain relief. Copyright 2005 British Journal of Surgery Society Ltd.
Authors: B Sacconi; R Argirò; Daniele Diacinti; A Iannarelli; M Bezzi; C Cipriani; D Pisani; V Cipolla; C De Felice; S Minisola; C Catalano Journal: Eur Radiol Date: 2015-05-31 Impact factor: 5.315
Authors: C E Ambrosini; L Cianferotti; A Picone; L Torregrossa; G Segnini; G Frustaci; F Cetani; F Basolo; C Marcocci; P Miccoli Journal: J Endocrinol Invest Date: 2011-10 Impact factor: 4.256
Authors: Celestino P Lombardi; Marco Raffaelli; Emanuela Traini; Carmela De Crea; Salvatore M Corsello; Rocco Bellantone Journal: World J Surg Date: 2009-11 Impact factor: 3.352
Authors: Anders O J Bergenfelz; Svante K G Jansson; Göran K Wallin; Hans G Mårtensson; Lars Rasmussen; Håkan L O Eriksson; Eva I M Reihnér Journal: Langenbecks Arch Surg Date: 2009-07-18 Impact factor: 3.445