Literature DB >> 15931377

Linkage disequilibrium maps and association mapping.

Newton E Morton1.   

Abstract

The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetics of LD, the maps and databases that it provides, and their use for association mapping, as well as alternative methods for gene localization, are briefly described.

Mesh：

Year:  2005        PMID： 15931377      PMCID： PMC1137007          DOI： 10.1172/JCI25032

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  25 in total

1.  High-resolution haplotype structure in the human genome.

Authors:  M J Daly; J D Rioux; S F Schaffner; T J Hudson; E S Lander
Journal:  Nat Genet       Date:  2001-10       Impact factor: 38.330

2.  Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex.

Authors:  A J Jeffreys; L Kauppi; R Neumann
Journal:  Nat Genet       Date:  2001-10       Impact factor: 38.330

3.  Genomics. New mapping project splits the community.

Authors:  Jennifer Couzin
Journal:  Science       Date:  2002-05-24       Impact factor: 47.728

4.  Properties of linkage disequilibrium (LD) maps.

Authors:  Weilhua Zhang; Andrew Collins; Nikolas Maniatis; William Tapper; Newton E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-16       Impact factor: 11.205

5.  The Human Genome Project in retrospect.

Authors:  Michael Abramowicz
Journal:  Adv Genet       Date:  2003       Impact factor: 1.944

6.  The impact of SNP density on fine-scale patterns of linkage disequilibrium.

Authors:  Xiayi Ke; Sarah Hunt; William Tapper; Robert Lawrence; George Stavrides; Jilur Ghori; Pamela Whittaker; Andrew Collins; Andrew P Morris; David Bentley; Lon R Cardon; Panos Deloukas
Journal:  Hum Mol Genet       Date:  2004-01-20       Impact factor: 6.150

7.  Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity.

Authors:  Andrew P Morris; John C Whittaker; Chun-Fang Xu; Louise K Hosking; David J Balding
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-03       Impact factor: 11.205

8.  Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes.

Authors:  Caroline Durrant; Krina T Zondervan; Lon R Cardon; Sarah Hunt; Panos Deloukas; Andrew P Morris
Journal:  Am J Hum Genet       Date:  2004-05-13       Impact factor: 11.025

9.  Positional cloning by linkage disequilibrium.

Authors:  Nikolas Maniatis; Andrew Collins; Jane Gibson; Weihua Zhang; William Tapper; Newton E Morton
Journal:  Am J Hum Genet       Date:  2004-03-26       Impact factor: 11.025

Review 10.  Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease.

Authors:  David Botstein; Neil Risch
Journal:  Nat Genet       Date:  2003-03       Impact factor: 38.330
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  10 in total

1.  Fine-scale map of encyclopedia of DNA elements regions in the Korean population.

Authors:  Yeon-Kyeong Yoo; Xiayi Ke; Sungwoo Hong; Hye-Yoon Jang; Kyunghee Park; Sook Kim; TaeJin Ahn; Yeun-Du Lee; Okryeol Song; Na-Young Rho; Moon Sue Lee; Yeon-Su Lee; Jaeheup Kim; Young J Kim; Jun-Mo Yang; Kyuyoung Song; Kyuchan Kimm; Bruce Weir; Lon R Cardon; Jong-Eun Lee; Jung-Joo Hwang
Journal:  Genetics       Date:  2006-05-15       Impact factor: 4.562

2.  Host susceptibility to persistent hepatitis B virus infection.

Authors:  Ying-Li He; Ying-Ren Zhao; Shu-Lin Zhang; Shu-Mei Lin
Journal:  World J Gastroenterol       Date:  2006-08-14       Impact factor: 5.742

Review 3.  Mapping the new frontier: complex genetic disorders.

Authors:  Richard Mayeux
Journal:  J Clin Invest       Date:  2005-06       Impact factor: 14.808

4.  Magnetic resonance imaging as a tool for in vivo and ex vivo anatomical phenotyping in experimental genetic models.

Authors:  Alain Pitiot; Zdenka Pausova; Malcolm Prior; Jennifer Perrin; Naomi Loyse; Tomás Paus
Journal:  Hum Brain Mapp       Date:  2007-06       Impact factor: 5.038

5.  Genetic dissection of adventitious shoot regeneration in roses by employing genome-wide association studies.

Authors:  Thi Hong Nhung Nguyen; Dietmar Schulz; Traud Winkelmann; Thomas Debener
Journal:  Plant Cell Rep       Date:  2017-06-24       Impact factor: 4.570

6.  High-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans.

Authors:  Winston Lau; Toby Andrew; Nikolas Maniatis
Journal:  Am J Hum Genet       Date:  2017-05-04       Impact factor: 11.025

7.  The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem.

Authors:  Mehdi Maadooliat; Naveen K Bansal; Jiblal Upadhya; Manzur R Farazi; Xiang Li; Max M He; Scott J Hebbring; Zhan Ye; Steven J Schrodi
Journal:  Front Genet       Date:  2016-12-12       Impact factor: 4.599

Review 8.  Microarray technology in obstetrics and gynecology: a guide for clinicians.

Authors:  Kenneth Ward
Journal:  Am J Obstet Gynecol       Date:  2006-04-17       Impact factor: 8.661

Review 9.  Genome-Environment Associations, an Innovative Tool for Studying Heritable Evolutionary Adaptation in Orphan Crops and Wild Relatives.

Authors:  Andrés J Cortés; Felipe López-Hernández; Matthew W Blair
Journal:  Front Genet       Date:  2022-08-05       Impact factor: 4.772

10.  Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits.

Authors:  Sachiko Isobe; Akihiro Nakaya; Satoshi Tabata
Journal:  DNA Res       Date:  2007-11-13       Impact factor: 4.458
  10 in total

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