Literature DB >> 15931296

Cyclooxygenase-2 inhibitors in gynecologic practice.

Thomas P Connolly1.   

Abstract

Treatment of pain and inflammation associated with dysmenorrhea, endometriosis, ovarian cancers and operative procedures is an ongoing challenge in gynecology. Understanding the roles of prostanoids and estrogen in these conditions and appropriate treatment approaches have advanced beyond traditional nonsteroidal anti-inflammatory drugs. In this article, the author describes some of the basic mechanisms of nonspecific nonsteroidal anti-inflammatory drugs and newer cyclooxygenase-2 inhibitors, especially as they are used in the obstetrics/gynecology practice.

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Year:  2003        PMID： 15931296      PMCID： PMC1069032          DOI： 10.3121/cmr.1.2.105

Source DB:  PubMed          Journal:  Clin Med Res        ISSN： 1539-4182


  29 in total

1.  Are COX-2 selective inhibitors nephrotoxic?

Authors:  M J Dunn
Journal:  Am J Kidney Dis       Date:  2000-05       Impact factor: 8.860

2.  Cyclooxygenase-2 inhibition and renal function.

Authors:  A K Pfister; R J Crisalli; W H Carter
Journal:  Ann Intern Med       Date:  2001-06-05       Impact factor: 25.391

Review 3.  Renal and related cardiovascular effects of conventional and COX-2-specific NSAIDs and non-NSAID analgesics.

Authors:  A Whelton
Journal:  Am J Ther       Date:  2000-03       Impact factor: 2.688

4.  Effects of celecoxib and naproxen on renal function in the elderly.

Authors:  A Whelton; G Schulman; C Wallemark; E J Drower; P C Isakson; K M Verburg; G S Geis
Journal:  Arch Intern Med       Date:  2000-05-22

5.  Effect of cyclooxygenase-2 inhibition on renal function in elderly persons receiving a low-salt diet. A randomized, controlled trial.

Authors:  S K Swan; D W Rudy; K C Lasseter; C F Ryan; K L Buechel; L J Lambrecht; M B Pinto; S C Dilzer; O Obrda; K J Sundblad; C P Gumbs; D L Ebel; H Quan; P J Larson; J I Schwartz; T A Musliner; B J Gertz; D C Brater; S L Yao
Journal:  Ann Intern Med       Date:  2000-07-04       Impact factor: 25.391

6.  Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial.

Authors:  L S Simon; A L Weaver; D Y Graham; A J Kivitz; P E Lipsky; R C Hubbard; P C Isakson; K M Verburg; S S Yu; W W Zhao; G S Geis
Journal:  JAMA       Date:  1999-11-24       Impact factor: 56.272

7.  Renin expression in COX-2-knockout mice on normal or low-salt diets.

Authors:  T Yang; Y Endo; Y G Huang; A Smart; J P Briggs; J Schnermann
Journal:  Am J Physiol Renal Physiol       Date:  2000-11

8.  The injectable cyclooxygenase-2-specific inhibitor parecoxib sodium has analgesic efficacy when administered preoperatively.

Authors:  P J Desjardins; E H Grossman; M E Kuss; S Talwalker; S Dhadda; D Baum; R C Hubbard
Journal:  Anesth Analg       Date:  2001-09       Impact factor: 5.108

9.  Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

Authors:  F E Silverstein; G Faich; J L Goldstein; L S Simon; T Pincus; A Whelton; R Makuch; G Eisen; N M Agrawal; W F Stenson; A M Burr; W W Zhao; J D Kent; J B Lefkowith; K M Verburg; G S Geis
Journal:  JAMA       Date:  2000-09-13       Impact factor: 56.272

Review 10.  COX-2 specific inhibitors offer improved advantages over traditional NSAIDs.

Authors:  M K Urban
Journal:  Orthopedics       Date:  2000-07       Impact factor: 1.390
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  3 in total

Review 1.  An evidence-based update on nonsteroidal anti-inflammatory drugs.

Authors:  C K S Ong; P Lirk; C H Tan; R A Seymour
Journal:  Clin Med Res       Date:  2007-03

2.  Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine.

Authors:  Birgit Waltenberger; Daniela Schuster; Sompol Paramapojn; Wandee Gritsanapan; Gerhard Wolber; Judith M Rollinger; Hermann Stuppner
Journal:  Phytomedicine       Date:  2010-09-20       Impact factor: 5.340

Review 3.  Impact of Dendrimers on Solubility of Hydrophobic Drug Molecules.

Authors:  Sonam Choudhary; Lokesh Gupta; Sarita Rani; Kaushalkumar Dave; Umesh Gupta
Journal:  Front Pharmacol       Date:  2017-05-16       Impact factor: 5.810
  3 in total

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