Literature DB >> 1592998

Recurrence rates of treated basal cell carcinomas. Part 3: Surgical excision.

M K Silverman1, A W Kopf, R S Bart, C M Grin, M S Levenstein.   

Abstract

This is the third report in a series that reviews the experience in the Skin and Cancer Unit, from 1955 through 1982, with the treatment of basal cell carcinomas (BCCs). It concerns 588 previously untreated (primary) BCCs removed by surgical excision. The cumulative 5-year recurrence rate was 4.8%. This is a statistically significant lower recurrence rate (P = .034) than 135 previously treated BCCs that had a re-recurrence rate of 11.6%. For the primary BCCs, multivariate analysis showed that location on the head (P = .010) and being male (P = .004) were independent risk factors for recurrence. The patient's age, the duration of the BCC, its maximum diameter, or the time span (1955-1963, 1964-1972, 1973-1982) in which it was treated did not significantly affect the recurrence rate. The 5-year recurrence rate for BCCs excised from various anatomic sites were as follows: 1) neck, trunk, and extremities = 0.7%; 2) head--less than 6 mm in diameter = 3.2%; 3) head--6 to 9 mm in diameter = 8.0% (treated since 1964 = 5.2%); and 4) head--10 mm or more in diameter = 9.0%. Surgical excision is a highly effective method for removal of BCCs, and achieved a good to excellent cosmetic outcome in about 85% of the recurrence-free treatment sites.

Entities:  

Mesh:

Year:  1992        PMID: 1592998     DOI: 10.1111/j.1524-4725.1992.tb03307.x

Source DB:  PubMed          Journal:  J Dermatol Surg Oncol        ISSN: 0148-0812


  38 in total

Review 1.  Basal cell carcinoma.

Authors:  C S M Wong; R C Strange; J T Lear
Journal:  BMJ       Date:  2003-10-04

2.  Expression of matrix metalloproteinase-1, -9, -13, and tissue inhibitor of metalloproteinases-1 in basal cell carcinomas of the eyelid.

Authors:  Zornitsa I Zlatarova; Ekaterina B Softova; Klara G Dokova; Elisabeth M Messmer
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Review 3.  Diagnosis and Management of Basal Cell Carcinoma.

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Journal:  Curr Treat Options Oncol       Date:  2019-02-11

4.  [Basal cell carcinoma of the face and scalp : An update on treatment options].

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Journal:  Pathologe       Date:  2018-09       Impact factor: 1.011

5.  Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment.

Authors:  Roberta Ruggeri; Andrea Maurichi; Maria Carla Tinti; Pierfrancesco Cadenelli; Roberto Patuzzo; Gianfrancesco Gallino; Mario Santinami
Journal:  Melanoma Manag       Date:  2015-02-25

6.  Unusual Presentation of Pigmented Basal Cell Carcinoma of Face: Surgical Challenge.

Authors:  Ravleen Nagi; Shashikant Sahu; Nitin Agarwal
Journal:  J Clin Diagn Res       Date:  2016-07-01

Review 7.  Needs assessment for Mohs micrographic surgery.

Authors:  Maryam M Asgari; Jonathan M Olson; Murad Alam
Journal:  Dermatol Clin       Date:  2012-01       Impact factor: 3.478

8.  Mohs micrographic surgery for periocular skin tumours in Ireland.

Authors:  M P Treacy; N C Wynne; J L Gale; E Duignan; B Moran; A M Flynn; P Ormond; R Barry; R Khan; P Moriarty; L Cassidy
Journal:  Ir J Med Sci       Date:  2015-07-11       Impact factor: 1.568

9.  Incompletely excised basal cell carcinomas: Our guidelines.

Authors:  P Longhi; M Paola Serra; E Robotti
Journal:  Onco Targets Ther       Date:  2008-07-01       Impact factor: 4.147

10.  Systemic therapy for inoperable and metastatic basal cell cancer.

Authors:  Leslie A Fecher
Journal:  Curr Treat Options Oncol       Date:  2013-06
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