Literature DB >> 1592676

Sch 42137, a novel antifungal antibiotic from an Actinoplanes sp. Fermentation, isolation, structure and biological properties.

R Cooper1, I Truumees, I Gunnarsson, D Loebenberg, A Horan, J Marquez, M Patel, V Gullo, M Puar, P Das.   

Abstract

A novel polycyclic xanthone, Sch 42137, related to the albofungin family of compounds was isolated from culture broth. Its structure was determined by detailed spectroscopic studies and comparison of circular dichroic studies to related compounds albofungin and simaomicin. Sch 42137 exhibited MIC values less than 0.125 micrograms/ml against yeasts and dermatophytes. Details are presented herein.

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Year:  1992        PMID: 1592676     DOI: 10.7164/antibiotics.45.444

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.

Authors:  Patrick Schwientek; Rafael Szczepanowski; Christian Rückert; Jörn Kalinowski; Andreas Klein; Klaus Selber; Udo F Wehmeier; Jens Stoye; Alfred Pühler
Journal:  BMC Genomics       Date:  2012-03-23       Impact factor: 3.969

Review 2.  Isolation, Biosynthesis, and Biological Activity of Polycyclic Xanthones From Actinomycetes.

Authors:  Hui-Qing Yu; Gang Li; Hong-Xiang Lou
Journal:  Front Microbiol       Date:  2022-07-13       Impact factor: 6.064

  2 in total

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