| Literature DB >> 15925819 |
Kenneth O Devaney1, Cynthia R Boschman, Sarah C Willard, Alfio Ferlito, Alessandra Rinaldo.
Abstract
Symptoms such as hearing impairment, tinnitus, or a disturbance in sense of balance can generally be attributed to non-neoplastic causes, such as otitis media, otosclerosis, or trauma. Less commonly, auricular signs and symptoms are the result of non-neoplastic and neoplastic space-occupying lesions. The external ear can be the site of development of squamous carcinomas and basal-cell carcinomas; the middle ear and inner ear can host metastatic deposits, and primary squamous carcinomas and adenocarcinomas. Most auricular malignant diseases occur in adulthood; only the rhabdomyosarcomas of the middle ear arise in children. Most malignant diseases of the auricular apparatus are treated by a combination of surgery (commonly including radical excision of temporal bone), radiotherapy, and chemotherapy.Entities:
Mesh:
Year: 2005 PMID: 15925819 DOI: 10.1016/S1470-2045(05)70208-4
Source DB: PubMed Journal: Lancet Oncol ISSN: 1470-2045 Impact factor: 41.316