Literature DB >> 1592573

Total lymphoid irradiation in chronic progressive multiple sclerosis.

R Capra1, N Marcianó, F Mattioli, V Di Monda, L A Vignolo, A Buffoli, E Micheletti, L Magno.   

Abstract

6 patients with severe chronic progressive multiple sclerosis were subjected to total lymphoid irradiation (TLI) to assess clinical efficacy and side effects. During a 4 year follow-up the disability progression was continuous. Side effects during TLI were well tolerated; side effects after TLI brought about a worsening of the quality of life. One patient died of pneumonia. In this preliminary study TLI did not reduce the worsening of disability in MS patients.

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Year:  1992        PMID： 1592573     DOI： 10.1007/bf02226961

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN： 0392-0461


  11 in total

1.  Long-term survival of skin allografts in mice treated with fractionated total lymphoid irradiation.

Authors:  S Slavin; S Strober; Z Fuks; H S Kaplan
Journal:  Science       Date:  1976-09-24       Impact factor: 47.728

2.  New diagnostic criteria for multiple sclerosis: guidelines for research protocols.

Authors:  C M Poser; D W Paty; L Scheinberg; W I McDonald; F A Davis; G C Ebers; K P Johnson; W A Sibley; D H Silberberg; W W Tourtellotte
Journal:  Ann Neurol       Date:  1983-03       Impact factor: 10.422

3.  T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis.

Authors:  K Ota; M Matsui; E L Milford; G A Mackin; H L Weiner; D A Hafler
Journal:  Nature       Date:  1990-07-12       Impact factor: 49.962

4.  Shared human T cell receptor V beta usage to immunodominant regions of myelin basic protein.

Authors:  K W Wucherpfennig; K Ota; N Endo; J G Seidman; A Rosenzweig; H L Weiner; D A Hafler
Journal:  Science       Date:  1990-05-25       Impact factor: 47.728

5.  Reporting results of cancer treatment.

Authors:  A B Miller; B Hoogstraten; M Staquet; A Winkler
Journal:  Cancer       Date:  1981-01-01       Impact factor: 6.860

6.  Effects of treatment on fertility in long-term survivors of childhood or adolescent cancer.

Authors:  J Byrne; J J Mulvihill; M H Myers; R R Connelly; M D Naughton; M R Krauss; S C Steinhorn; D D Hassinger; D F Austin; K Bragg
Journal:  N Engl J Med       Date:  1987-11-19       Impact factor: 91.245

7.  Total lymphoid irradiation for multiple sclerosis.

Authors:  C K Devereux; R Vidaver; M P Hafstein; G Zito; R Troiano; P C Dowling; S D Cook
Journal:  Int J Radiat Oncol Biol Phys       Date:  1988-01       Impact factor: 7.038

8.  Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS).

Authors:  J F Kurtzke
Journal:  Neurology       Date:  1983-11       Impact factor: 9.910

9.  Total lymphoid irradiation in multiple sclerosis: blood lymphocytes and clinical course.

Authors:  S D Cook; C Devereux; R Troiano; G Zito; M Hafstein; M Lavenhar; E Hernandez; P C Dowling
Journal:  Ann Neurol       Date:  1987-11       Impact factor: 10.422

10.  Effect of total lymphoid irradiation in chronic progressive multiple sclerosis.

Authors:  S D Cook; C Devereux; R Troiano; M P Hafstein; G Zito; E Hernandez; M Lavenhar; R Vidaver; P C Dowling
Journal:  Lancet       Date:  1986-06-21       Impact factor: 79.321
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