| Literature DB >> 15924916 |
Michael G Knott1, Henry Mkwananzi, Catherine E Arendse, Denver T Hendricks, John J Bolton, Denzil R Beukes.
Abstract
Three new polyhalogenated monoterpenes, plocoralides A-C (1-3) along with three known compounds (4-6) have been isolated from the organic extract of the red alga P. corallorhiza. Structures of the new compounds were characterized as 4,8-dibromo-1,1-dichloro-3,7-dimethyl-2E,6E-octadiene (1), 4,6-dibromo-1,1-dichloro-3,7-dimethyl-2E,7-octadiene (2) and 4,8-dibromo-1,1,7-trichloro-3,7-dimethyl-2E,5Z-octadiene (3) on the basis of one- and two-dimensional NMR spectroscopic data and MS analyses. Compounds 2-6 show moderate cytotoxicity toward esophageal cancer cells.Entities:
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Year: 2005 PMID： 15924916 DOI： 10.1016/j.phytochem.2005.03.029
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072