Literature DB >> 1592444

The influence of the In(Lu) gene on expression of CDw75 antigens on human red blood cells.

K Guy1, C Green.   

Abstract

The influence of the In(Lu) gene on human red blood cell (RBC) expression of CDw75 antigens was examined. CDw75 antigens were increased in expression on Lu(a-b-) cells of the dominant inhibitor type in comparison with red cells from donors of other Lutheran (Lu) phenotypes. In contrast, CD44 epitopes detected with F10-44-2, A3D8 and BU52 monoclonal antibodies (mAb) were decreased in expression on Lu(a-b-) red cells. Among normal blood donors of the common phenotype Lu(a-b+) there was a wide range of expression of CDw75 antigens on red cells. The results show that CDw75 is a quantitative polymorphism of human red cells and, among antigens influenced by the In(Lu) gene, is unique in being up-regulated in expression.

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Year:  1992        PMID： 1592444      PMCID： PMC1384856     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  10 in total

1.  Expression of the CDw75 (beta-galactoside alpha 2,6-sialyltransferase) antigen on normal blood cells and in B-cell chronic lymphocytic leukaemia.

Authors:  K Guy; J M Andrew
Journal:  Immunology       Date:  1991-10       Impact factor: 7.397

2.  Antigens Aua, i and P1 of cells of the dominant type of Lu(a-b-).

Authors:  M N Crawford; P Tippett; R Sanger
Journal:  Vox Sang       Date:  1974-03       Impact factor: 2.144

Review 3.  Blood group ABH and Ii antigens of human erythrocytes: chemistry, polymorphism, and their developmental change.

Authors:  S Hakomori
Journal:  Semin Hematol       Date:  1981-01       Impact factor: 3.851

Review 4.  The P blood group system: recent progress in immunochemistry and genetics.

Authors:  D M Marcus; S K Kundu; A Suzuki
Journal:  Semin Hematol       Date:  1981-01       Impact factor: 3.851

5.  Enzymatic and organizational difference in expression of a Burkitt lymphoma-associated antigen (globotriaosylceramide) in Burkitt lymphoma and lymphoblastoid cell lines.

Authors:  J Wiels; E H Holmes; N Cochran; T Tursz; S Hakomori
Journal:  J Biol Chem       Date:  1984-12-10       Impact factor: 5.157

6.  Evidence that the Lub blood group antigen is located on red cell membrane glycoproteins of 85 and 78 kd.

Authors:  S F Parsons; G Mallinson; P A Judson; D J Anstee; M J Tanner; G L Daniels
Journal:  Transfusion       Date:  1987 Jan-Feb       Impact factor: 3.157

7.  Sialylation of glycoprotein oligosaccharides N-linked to asparagine. Enzymatic characterization of a Gal beta 1 to 3(4)GlcNAc alpha 2 to 3 sialyltransferase and a Gal beta 1 to 4GlcNAc alpha 2 to 6 sialyltransferase from rat liver.

Authors:  J Weinstein; U de Souza-e-Silva; J C Paulson
Journal:  J Biol Chem       Date:  1982-11-25       Impact factor: 5.157

8.  Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene.

Authors:  M J Telen; G S Eisenbarth; B F Haynes
Journal:  J Clin Invest       Date:  1983-06       Impact factor: 14.808

9.  The Ina and Inb blood group antigens are located on a glycoprotein of 80,000 MW (the CDw44 glycoprotein) whose expression is influenced by the In(Lu) gene.

Authors:  F A Spring; R Dalchau; G L Daniels; G Mallinson; P A Judson; S F Parsons; J W Fabre; D J Anstee
Journal:  Immunology       Date:  1988-05       Impact factor: 7.397

10.  The B cell antigen CD75 is a cell surface sialytransferase.

Authors:  I Stamenkovic; H C Asheim; A Deggerdal; H K Blomhoff; E B Smeland; S Funderud
Journal:  J Exp Med       Date:  1990-08-01       Impact factor: 14.307
  10 in total
  1 in total

1.  Second Jenner international glycoimmunology meeting.

Authors: 
Journal:  Ann Rheum Dis       Date:  1992-11       Impact factor: 19.103
  1 in total

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