| Literature DB >> 15924299 |
Maria Martinez1, Alexis Brice, Jenny R Vaughan, Alexander Zimprich, Monique M B Breteler, Giuseppe Meco, Alessandro Filla, Matthew J Farrer, Christine Bétard, Andrew Singleton, John Hardy, Giuseppe De Michele, Vincenzo Bonifati, Ben A Oostra, Thomas Gasser, Nick W Wood, Alexandra Dürr.
Abstract
Analysis of the apolipoprotein E genotype in sibpairs with Parkinson's disease showed the E4 allele was over represented in those who shared the adjacent chromosome 19 markers. This suggests that apolipoprotein E4 is responsible for the linkage peak in this region and that it is a modest risk factor for Parkinson's disease. Copyright 2005 Wiley-Liss, Inc.Entities:
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Year: 2005 PMID： 15924299 DOI： 10.1002/ajmg.b.30196
Source DB: PubMed Journal: Am J Med Genet B Neuropsychiatr Genet ISSN： 1552-4841 Impact factor: 3.568