| Literature DB >> 15922843 |
Patrick Angibaud1, Janine Arts, Kristof Van Emelen, Virginie Poncelet, Isabelle Pilatte, Bruno Roux, Sven Van Brandt, Marc Verdonck, Hans De Winter, Peter Ten Holte, Ann Marien, Wim Floren, Boudewijn Janssens, Jacky Van Dun, An Aerts, Jacky Van Gompel, Sandrine Gaurrand, Laurence Queguiner, Jean-Michel Argoullon, Luc Van Hijfte, Eddy Freyne, Michel Janicot.
Abstract
A series of pyrimidyl-5-hydroxamic acids was prepared for evaluation as inhibitors of histone deacetylase (HDAC). Amino-2-pyrimidinyl can be used as a linker to provide HDAC inhibitors of good enzymatic potency.Entities:
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Year: 2005 PMID： 15922843 DOI： 10.1016/j.ejmech.2005.01.008
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514