Literature DB >> 15922822

Quantifying the use of the statin antilipemic drugs: comparisons and contrasts between Nova Scotia, Canada, and Queensland, Australia.

Charmaine Cooke1, Lisa Nissen, Ingrid Sketris, Susan E Tett.   

Abstract

BACKGROUND: Jurisdictions are developing public drug insurance systems to improve access to pharmaceuticals, cost-effective prescribing, and patient health and well-being. We compared 2 jurisdictions with different pharmaceutical policies to determine prescribing patterns for 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (ie, statins).
OBJECTIVE: The aim of this work was to investigate the feasibility of using available prescription administrative databases to compare the use of statins in Queensland, Australia, and in Nova Scotia, Canada.
METHODS: Data from the Nova Scotia Pharmacare Program and the Health Insurance Commission in Australia were used to obtain dispensing data. Utilization was compared for the 5-year period from 1997 through 2001, using the World Health Organization anatomic therapeutic chemical/defined daily dose (DDD) system.
RESULTS: In the year 2001, there were 177,000 beneficiaries in the public drug plan in Nova Scotia (62% aged > or = 65 years old) and 960,000 concession beneficiaries (pensioners and social security recipients, 61 aged > or = 65 years) in Queensland. These 2 groups were comparable. The overall utilization of statin medications increased steadily in both areas over the study period, from 50 to 205 DDD/1000 beneficiaries per day. Comparison of the 2 growth lines showed no statistically significant differences in overall statin use despite differences in brand availabilities and policies about prescribing. In the year 2001, atorvastatin was the most commonly prescribed statin in both areas, comprising 46% of statin use in Nova Scotia and 51% in Queensland. Mean doses of each statin prescribed were slightly above the DDDs. Expenditure on statins per 1000 beneficiaries and per DDD were similar in each jurisdiction, being slightly higher in Nova Scotia.
CONCLUSIONS: Despite differences in pharmaceutical reimbursement systems, use of the statins was similar in Nova Scotia and Queensland. The feasibility of the methodology was demonstrated. Future studies, including comparisons of drug utilization for other classes of drugs for which drug policies may be divergent (eg, different pricing structures or prior authorization requirements), or for which less evidence for appropriate use is available, may be useful.

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Year:  2005        PMID: 15922822     DOI: 10.1016/j.clinthera.2005.04.009

Source DB:  PubMed          Journal:  Clin Ther        ISSN: 0149-2918            Impact factor:   3.393


  5 in total

1.  Comparison of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 (COX-2) inhibitors use in Australia and Nova Scotia (Canada).

Authors:  Nadia Barozzi; Ingrid Sketris; Charmaine Cooke; Susan Tett
Journal:  Br J Clin Pharmacol       Date:  2009-07       Impact factor: 4.335

2.  Efficacy and tolerability of ezetimibe 10 mg/day coadministered with statins in patients with primary hypercholesterolemia who do not achieve target LDL-C while on statin monotherapy: A Canadian, multicentre, prospective study--the Ezetrol Add-On Study.

Authors:  Stéphane Bissonnette; Rafik Habib; Fotini Sampalis; Stella Boukas; John S Sampalis
Journal:  Can J Cardiol       Date:  2006-10       Impact factor: 5.223

3.  The impact of statins on health services utilization and mortality in older adults discharged from hospital with ischemic heart disease: a cohort study.

Authors:  Charmaine A Cooke; Susan A Kirkland; Ingrid S Sketris; Jafna Cox
Journal:  BMC Health Serv Res       Date:  2009-11-04       Impact factor: 2.655

4.  Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model.

Authors:  John S Sampalis; Stéphane Bissonnette; Stella Boukas
Journal:  Adv Prev Med       Date:  2010-10-31

5.  Non-steroidal anti-inflammatory drugs, Cyclooxygenase-2 inhibitors and paracetamol use in Queensland and in the whole of Australia.

Authors:  Nadia Barozzi; Susan E Tett
Journal:  BMC Health Serv Res       Date:  2008-09-24       Impact factor: 2.655

  5 in total

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