Literature DB >> 15922077

Clues to function in gene deserts.

James Taylor1.   

Abstract

Recent work by Ivan Ovcharenko and colleagues has shed new light on the functional importance of gene deserts. They demonstrate that sequence conservation levels separate gene deserts into stable (more conserved) and variable classes. Both classes exhibit characteristics suggestive of function. The stable deserts in particular show features suggesting a role in the complex regulation of core vertebrate genes.

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Year:  2005        PMID： 15922077     DOI： 10.1016/j.tibtech.2005.04.003

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  9 in total

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Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

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Journal:  PLoS Genet       Date:  2016-11-10       Impact factor: 5.917

5.  Super-enhancers in transcriptional regulation and genome organization.

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Journal:  Nucleic Acids Res       Date:  2019-12-16       Impact factor: 16.971

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7.  Nonconserved Long Intergenic Noncoding RNAs Associate With Complex Cardiometabolic Disease Traits.

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8.  Subfunctionalization of duplicated zebrafish pax6 genes by cis-regulatory divergence.

Authors:  Dirk A Kleinjan; Ruth M Bancewicz; Philippe Gautier; Ralf Dahm; Helia B Schonthaler; Giuseppe Damante; Anne Seawright; Ann M Hever; Patricia L Yeyati; Veronica van Heyningen; Pedro Coutinho
Journal:  PLoS Genet       Date:  2008-02       Impact factor: 5.917

9.  Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin.

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Journal:  BMC Genomics       Date:  2013-12-28       Impact factor: 3.969
  9 in total

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