Literature DB >> 15921710

An anti-staphylococcal acylphloroglucinol from Hypericum foliosum.

Simon Gibbons1, Elisabeth Moser, Sebastian Hausmann, Michael Stavri, Eileen Smith, Christopher Clennett.   

Abstract

An investigation into the antibacterial properties of Hypericum foliosum Aiton. (Guttiferae) has led to the isolation of a new bioactive acylphloroglucinol natural product which by NMR spectroscopy and mass spectrometry was characterised as 1,3,5-trihydroxy-6-[2''',3'''-epoxy-3'''-methyl-butyl]-2-[2''-methyl-butanoyl]-4-[3'-methyl-2''-butenyl]-benzene and is described here for the first time. This metabolite was evaluated against a panel of multidrug-resistant strains of Staphylococcus aureus and minimum inhibitory values ranged from 16 to 32 microg/ml.

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Year:  2005        PMID： 15921710     DOI： 10.1016/j.phytochem.2005.04.024

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  9 in total

1.  A new acylphloroglucinol glycoside from Solidago altissima L.

Authors:  Haili Jin; Keiko Ogino; Toshihiro Fujioka; Miyako Yoshida; Kanji Ishimaru
Journal:  J Nat Med       Date:  2007-11-17       Impact factor: 2.343

2.  Inhibition of bacterial growth and biofilm production by constituents from Hypericum spp.

Authors:  S A Sarkisian; M J Janssen; H Matta; G E Henry; K L Laplante; D C Rowley
Journal:  Phytother Res       Date:  2011-12-15       Impact factor: 5.878

3.  Hypericum in infection: Identification of anti-viral and anti-inflammatory constituents.

Authors:  Diane F Birt; Mark P Widrlechner; Kimberly Dp Hammer; Matthew L Hillwig; Jingqiang Wei; George A Kraus; Patricia A Murphy; Joeann McCoy; Eve S Wurtele; Jeffrey D Neighbors; David F Wiemer; Wendy J Maury; Jason P Price
Journal:  Pharm Biol       Date:  2009       Impact factor: 3.503

4.  Identification and biosynthesis of acylphloroglucinols in Hypericum gentianoides.

Authors:  Matthew C Crispin; Manhoi Hur; Taeseong Park; Young Hwan Kim; Eve Syrkin Wurtele
Journal:  Physiol Plant       Date:  2013-05-24       Impact factor: 4.500

5.  Morphological and Phytochemical Diversity among Hypericum Species of the Mediterranean Basin.

Authors:  Nicolai M Nürk; Sara L Crockett
Journal:  Med Aromat Plant Sci Biotechnol       Date:  2011-01

6.  Anti-proliferative and anti-migration effects of Polish propolis combined with Hypericum perforatum L. on glioblastoma multiforme cell line U87MG.

Authors:  Maria H Borawska; Sylwia K Naliwajko; Justyna Moskwa; Renata Markiewicz-Żukowska; Anna Puścion-Jakubik; Jolanta Soroczyńska
Journal:  BMC Complement Altern Med       Date:  2016-09-20       Impact factor: 3.659

7.  Antimicrobial and antioxidant activities of the extracts and compounds from the leaves of Psorospermum aurantiacum Engl. and Hypericum lanceolatum Lam.

Authors:  Patricia D Tchakam; Paul K Lunga; Théodora K Kowa; Antoine Honoré N Lonfouo; Hippolyte K Wabo; Léon A Tapondjou; Pierre Tane; Jules-Roger Kuiate
Journal:  BMC Complement Altern Med       Date:  2012-08-24       Impact factor: 3.659

8.  Dermatological remedies in the traditional pharmacopoeia of Vulture-Alto Bradano, inland southern Italy.

Authors:  Cassandra L Quave; Andrea Pieroni; Bradley C Bennett
Journal:  J Ethnobiol Ethnomed       Date:  2008-02-06       Impact factor: 2.733

9.  Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication.

Authors:  Cinzia Sanna; Monica Scognamiglio; Antonio Fiorentino; Angela Corona; Vittoria Graziani; Alessia Caredda; Pierluigi Cortis; Mariofilippo Montisci; Elisa Rita Ceresola; Filippo Canducci; Ferruccio Poli; Enzo Tramontano; Francesca Esposito
Journal:  PLoS One       Date:  2018-03-30       Impact factor: 3.240
  9 in total

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