Literature DB >> 15920622

Functional characterization of KlHEM13, a hypoxic gene of Kluyveromyces lactis.

Moisés Blanco1, Manuel Becerra, M Isabel González-Siso, M Esperanza Cerdán.   

Abstract

The KlHEM13 gene of Kluyveromyces lactis encoding the coproporphyrinogen oxidase (EC 1.3.3.3), an oxygen-requiring enzyme that catalyzes the sixth step of heme biosynthesis, was cloned and functionally characterized. The coding and upstream regions of KlHEM13 were analyzed and the putative cis regulatory elements were discussed in relation to the mechanisms of regulation of this hypoxic gene in K. lactis.

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Year:  2005        PMID： 15920622     DOI： 10.1139/w04-133

Source DB:  PubMed          Journal:  Can J Microbiol        ISSN： 0008-4166            Impact factor:   2.419


  6 in total

1.  Two proteins with different functions are derived from the KlHEM13 gene.

Authors:  Angel Vizoso Vázquez; Moisés Blanco; Justyna Zaborowska; Pilar Soengas; M Isabel González-Siso; Manuel Becerra; Esther Rodríguez-Belmonte; M Esperanza Cerdán
Journal:  Eukaryot Cell       Date:  2011-08-05

2.  Proteome analysis of soybean roots under waterlogging stress at an early vegetative stage.

Authors:  Iftekhar Alam; Dong-Gi Lee; Kyung-Hee Kim; Choong-Hoon Park; Shamima Akhtar Sharmin; Hyoshin Lee; Ki-Won Oh; Byung-Wook Yun; Byung-Hyun Lee
Journal:  J Biosci       Date:  2010-03       Impact factor: 1.826

Review 3.  Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi.

Authors:  Angelique C W Franken; B Christien Lokman; Arthur F J Ram; Peter J Punt; Cees A M J J van den Hondel; Sandra de Weert
Journal:  Appl Microbiol Biotechnol       Date:  2011-06-18       Impact factor: 4.813

Review 4.  Kluyveromyces lactis: a suitable yeast model to study cellular defense mechanisms against hypoxia-induced oxidative stress.

Authors:  M Isabel González Siso; M Esperanza Cerdán
Journal:  Oxid Med Cell Longev       Date:  2012-07-02       Impact factor: 6.543

5.  Role of hypoxia-inducible factor-1α in pathogenesis and disease evaluation of ulcerative colitis.

Authors:  Chunmei Xu; Weiguo Dong
Journal:  Exp Ther Med       Date:  2016-01-28       Impact factor: 2.447

6.  The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis.

Authors:  Agustín Rico-Díaz; Aída Barreiro-Alonso; Cora Rey-Souto; Manuel Becerra; Mónica Lamas-Maceiras; M Esperanza Cerdán; Ángel Vizoso-Vázquez
Journal:  Biomolecules       Date:  2021-09-21
  6 in total

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