Literature DB >> 15920407

Functional status after childhood traumatic brain injury.

Barbara Wechsler1, Heakyung Kim, Paul R Gallagher, Carla DiScala, Margaret G Stineman.   

Abstract

BACKGROUND: Identification of children after traumatic brain injury (TBI) likely to have functional deficits at trauma center discharge will facilitate care.
METHODS: Two logistic regression models were derived from data on 4,439 children after TBI 7 to 14 years old enrolled in the National Pediatric Trauma Registry between 1994 and 2001 to predict physical and cognitive disabilities.
RESULTS: Children with open or multiple fractures or closed fractures or injured by motor vehicles were 8.2, 3.5, or 2.5 times more likely, respectively, than those without those circumstances to have discharge physical disabilities. Likelihood of cognitive impairment was increased by factors of 3.2 and 5.8 in children obtunded or comatose on arrival. Preexisting cognitive deficits, injury severity, and intubation predicted physical and cognitive disabilities. The C statistic was 0.862 for the motor model and 0.860 for the cognitive model.
CONCLUSION: Predicting the likelihood of morbidity after acute management of childhood TBI can provide information pertinent to providing effective care.

Entities:  

Mesh:

Year:  2005        PMID: 15920407     DOI: 10.1097/01.ta.0000162630.78386.98

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  10 in total

Review 1.  L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain.

Authors:  Gustavo C Ferreira; Mary C McKenna
Journal:  Neurochem Res       Date:  2017-05-16       Impact factor: 3.996

Review 2.  Progesterone for neuroprotection in pediatric traumatic brain injury.

Authors:  Courtney L Robertson; Emin Fidan; Rachel M Stanley; Corina Noje; Hülya Bayir
Journal:  Pediatr Crit Care Med       Date:  2015-03       Impact factor: 3.624

3.  Progesterone protects mitochondrial function in a rat model of pediatric traumatic brain injury.

Authors:  Courtney L Robertson; Manda Saraswati
Journal:  J Bioenerg Biomembr       Date:  2014-10-28       Impact factor: 2.945

4.  Evidence for impaired plasticity after traumatic brain injury in the developing brain.

Authors:  Nan Li; Ya Yang; David P Glover; Jiangyang Zhang; Manda Saraswati; Courtney Robertson; Galit Pelled
Journal:  J Neurotrauma       Date:  2013-12-10       Impact factor: 5.269

Review 5.  Metabolic Alterations in Developing Brain After Injury: Knowns and Unknowns.

Authors:  Mary C McKenna; Susanna Scafidi; Courtney L Robertson
Journal:  Neurochem Res       Date:  2015-07-07       Impact factor: 3.996

6.  Physical disability after injury-related inpatient rehabilitation in children.

Authors:  Mark R Zonfrillo; Dennis R Durbin; Flaura K Winston; Huaqing Zhao; Margaret G Stineman
Journal:  Pediatrics       Date:  2012-12-17       Impact factor: 7.124

Review 7.  Mitochondrial mechanisms of cell death and neuroprotection in pediatric ischemic and traumatic brain injury.

Authors:  Courtney L Robertson; Susanna Scafidi; Mary C McKenna; Gary Fiskum
Journal:  Exp Neurol       Date:  2009-05-07       Impact factor: 5.330

8.  Residual cognitive disability after completion of inpatient rehabilitation among injured children.

Authors:  Mark R Zonfrillo; Dennis R Durbin; Flaura K Winston; Xuemei Zhang; Margaret G Stineman
Journal:  J Pediatr       Date:  2013-10-24       Impact factor: 4.406

9.  Metabolism of Exogenous [2,4-13C]β-Hydroxybutyrate following Traumatic Brain Injury in 21-22-Day-Old Rats: An Ex Vivo NMR Study.

Authors:  Susanna Scafidi; Jennifer Jernberg; Gary Fiskum; Mary C McKenna
Journal:  Metabolites       Date:  2022-07-29

10.  Transcranial magnetic stimulation facilitates neurorehabilitation after pediatric traumatic brain injury.

Authors:  Hongyang Lu; Tali Kobilo; Courtney Robertson; Shanbao Tong; Pablo Celnik; Galit Pelled
Journal:  Sci Rep       Date:  2015-10-06       Impact factor: 4.379

  10 in total

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