| Literature DB >> 15919727 |
Anke Busch1, Sebastian Will, Rolf Backofen.
Abstract
SUMMARY: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli. AVAILABILITY: The server is available at http://www.bio.inf.uni-jena.de/Software/SECISDesign/index.html.Entities:
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Year: 2005 PMID: 15919727 DOI: 10.1093/bioinformatics/bti507
Source DB: PubMed Journal: Bioinformatics ISSN: 1367-4803 Impact factor: 6.937