| Literature DB >> 15918410 |
L Di Giovannantonio1, R Bellocci, R Zappacosta, B Zappacosta, A Castrataro, M Liberatore, M Liberati, D Angelucci.
Abstract
Malignant tumors of peripheral nerves (MPNST) represent approximately 5-10% of all soft tissue sarcomas and usually are in relationship with a major nerve. Primary cervical malignant Schwannomas are very rare neural sheat tumors that, grossly and clinically, are misdiagnosed for other more frequent lesions of the uterine cervix. We report a case of primary cervical malignant Schwannoma in a 27 years old female with atypical bleeding. The lesion is characterized by densely packed spindle cells with nuclear atypia and high mitotic rate. Immuno-histochemical stains are positive for vimentin and S-100 but negative for HMB-45, keratins, desmin and actin. After 34 months the patient is disease free. To our knowledge, this is the seventh case described.Entities:
Mesh:
Year: 2005 PMID: 15918410
Source DB: PubMed Journal: Pathologica ISSN: 0031-2983