Literature DB >> 15918210

Atorvastatin-induced severe gastric ulceration: a case report.

Ihab I El-Hajj1, Fadi H Mourad, Nina S Shabb, Kassem A Barada.   

Abstract

A 41-year-old man presented with severe gastric ulceration 3 mo after beginning treatment with atorvastatin 20 mg once daily for hypercholesterolemia. The patient was not taking any ulcerogenic drugs and had no evidence of Helicobacter pylori infection. Proton pump inhibitor therapy was initiated and atorvastatin was replaced by simvastatin with complete resolution of gastrointestinal symptoms. To our knowledge, this is the first report of atorvastatin-induced gastric ulceration, which should be looked for in patients who develop abdominal pain while on this drug.

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Year:  2005        PMID： 15918210      PMCID： PMC4305860          DOI： 10.3748/wjg.v11.i20.3159

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  16 in total

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Journal:  Arch Ophthalmol       Date:  2000-03

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Journal:  Ann Pharmacother       Date:  2001-10       Impact factor: 3.154

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Journal:  J Am Board Fam Pract       Date:  2001 Mar-Apr

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Authors:  Alan S Segal
Journal:  Am J Med       Date:  2002-08-01       Impact factor: 4.965

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Authors:  Helmut Sinzinger
Journal:  Wien Klin Wochenschr       Date:  2002-11-30       Impact factor: 1.704

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Journal:  Lancet       Date:  1998-10-17       Impact factor: 79.321

8.  Toxic epidermal necrolysis from atorvastatin.

Authors:  C M Pfeiffer; S Kazenoff; H D Rothberg
Journal:  JAMA       Date:  1998-05-27       Impact factor: 56.272

Review 9.  Atorvastatin: a hydroxymethylglutaryl-coenzyme A reductase inhibitor.

Authors:  J M Malinowski
Journal:  Am J Health Syst Pharm       Date:  1998-11-01       Impact factor: 2.637

Review 10.  [Adverse effects of statins].

Authors:  Michel Andréjak; Valérie Gras; Ziad A Massy; Jacques Caron
Journal:  Therapie       Date:  2003 Jan-Feb       Impact factor: 2.070
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  3 in total

Review 1.  Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism.

Authors:  Beatrice A Golomb; Marcella A Evans
Journal:  Am J Cardiovasc Drugs       Date:  2008       Impact factor: 3.571

2.  Effect of Statins on Helicobacter pylori Eradication Rate: A Systematic Review and Meta-Analysis.

Authors:  Mohsen Rajabnia; Amir Sadeghi; Saeed Abdi; Mihnea-Alexandru Găman; Mohammad Reza Zali; Niloufar Salehi; Abbas Yadegar; Khaled Rahmani
Journal:  GE Port J Gastroenterol       Date:  2021-09-06

3.  [18F]Atorvastatin Pharmacokinetics and Biodistribution in Healthy Female and Male Rats.

Authors:  Gonçalo S Clemente; Inês F Antunes; Jürgen W A Sijbesma; Aren van Waarde; Adriaan A Lammertsma; Alexander Dömling; Philip H Elsinga
Journal:  Mol Pharm       Date:  2021-08-05       Impact factor: 4.939
  3 in total

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