Literature DB >> 15917555

Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro.

Tsutomu Yamazaki1, Toshio Kishimoto, Sadashi Shiga, Kozue Sato, Toshikatsu Hagiwara, Miyuki Inoue, Nozomu Sasaki, Kazunobu Ouchi, Yukihiko Hara.   

Abstract

Biosynthesized tea polyphenols showed antichlamydial activity against Chlamydia trachomatis D/UW-3/Cx and L2/434/Bu using cell culture. The most active compounds were (-)-epigallocatechin gallate and (-)-epicatechin gallate, followed by (-)-epicatechin (EC). (+)-Epicatechin and (-)-epigallocatechin were intermediate. EC was the least toxic. These results warrant evaluation of tea polyphenols as topical antichlamydial agents.

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Year:  2005        PMID： 15917555      PMCID： PMC1140499          DOI： 10.1128/AAC.49.6.2501-2503.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  In vitro microbicidal activities of cecropin peptides D2A21 and D4E1 and gel formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis.

Authors:  L M Ballweber; J E Jaynes; W E Stamm; M F Lampe
Journal:  Antimicrob Agents Chemother       Date:  2002-01       Impact factor: 5.191

2.  The microbicidal agent C31G inhibits Chlamydia trachomatis infectivity in vitro.

Authors:  P B Wyrick; S T Knight; D G Gerbig; J E Raulston; C H Davis; T R Paul; D Malamud
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

3.  The protective activity of tea against infection by Vibrio cholerae O1.

Authors:  M Toda; S Okubo; H Ikigai; T Suzuki; Y Suzuki; T Shimamura
Journal:  J Appl Bacteriol       Date:  1991-02

4.  Chlamydia trachomatis genital infections--United States, 1995.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1997-03-07       Impact factor: 17.586

5.  Susceptibility of Chlamydia trachomatis to protegrins and defensins.

Authors:  B Yasin; S S Harwig; R I Lehrer; E A Wagar
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441

6.  Reducing the risk of Chlamydia trachomatis genital tract infection by evaluating the prophylactic potential of vaginally applied chemicals.

Authors:  J M Lyons; J I Ito
Journal:  Clin Infect Dis       Date:  1995-10       Impact factor: 9.079

7.  Inhibition of the infectivity of influenza virus by tea polyphenols.

Authors:  M Nakayama; K Suzuki; M Toda; S Okubo; Y Hara; T Shimamura
Journal:  Antiviral Res       Date:  1993-08       Impact factor: 5.970

8.  Bactericidal catechins damage the lipid bilayer.

Authors:  H Ikigai; T Nakae; Y Hara; T Shimamura
Journal:  Biochim Biophys Acta       Date:  1993-04-08

9.  In vitro activity of the spermicide nonoxynol-9 against Chlamydia trachomatis.

Authors:  J P Kelly; R B Reynolds; S Stagno; W C Louv; W J Alexander
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

10.  In vitro inhibitory effects of tea polyphenols on the proliferation of Chlamydia trachomatis and Chlamydia pneumoniae.

Authors:  Tsutomu Yamazaki; Miyuki Inoue; Nozomu Sasaki; Toshikatsu Hagiwara; Toshio Kishimoto; Sadashi Shiga; Motohiko Ogawa; Yukihiko Hara; Takaaki Matsumoto
Journal:  Jpn J Infect Dis       Date:  2003-08       Impact factor: 1.362
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  2 in total

1.  In vitro inhibitory effect of Hydrocotyle bonariensis Lam. extracts over Chlamydia trachomatis and Chlamydia pneumoniae on different stages of the chlamydial life cycle.

Authors:  Andrea Carolina Entrocassi; Alejandra Vanina Catalano; Adriana Graciela Ouviña; Erica Georgina Wilson; Paula Gladys López; Marcelo Rodríguez Fermepin
Journal:  Heliyon       Date:  2021-05-18

Review 2.  Natural Products for the Treatment of Chlamydiaceae Infections.

Authors:  Mika A Brown; Michael G Potroz; Seoh-Wei Teh; Nam-Joon Cho
Journal:  Microorganisms       Date:  2016-10-16
  2 in total

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