| Literature DB >> 15917423 |
J Sutak1, J S Armstrong, J E Rusby.
Abstract
Transformation of differentiated thyroid cancer into poorly differentiated carcinoma is rare. This report describes a case in which preoperative fine needle aspiration suggested a squamous cell carcinoma whereas needle core biopsy favoured an undifferentiated carcinoma of probable thyroid origin. Histology of the subsequent total thyroidectomy specimen revealed a biphasic tumour comprising areas of tall cell papillary carcinoma merging with moderately to poorly differentiated squamous cell carcinoma. The immunohistochemical findings are discussed in detail.Entities:
Mesh:
Year: 2005 PMID: 15917423 PMCID: PMC1770674 DOI: 10.1136/jcp.2004.021451
Source DB: PubMed Journal: J Clin Pathol ISSN: 0021-9746 Impact factor: 3.411