Literature DB >> 15916896

N,N'-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single pyrimidine bulge in duplex DNA.

Hitoshi Suda1, Akio Kobori, Jinhua Zhang, Gosuke Hayashi, Kazuhiko Nakatani.   

Abstract

We here show the first identified ligand 2,7-diamino-1,8-naphthyridine (DANP) that strongly and specifically binds to the single cytosine and thymine bulges with exclusively 1:1 stoichiometry.

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Year:  2005        PMID： 15916896     DOI： 10.1016/j.bmc.2005.04.035

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  3 in total

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Authors:  Kazuhiko Nakatani
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2022       Impact factor: 3.493

2.  Tuning the sensitivity towards mercury via cooperative binding to d-fructose: dual fluorescent chemosensor based on 1,8-naphthyridine-boronic acid derivative.

Authors:  Marina Rajadurai; E Ramanjaneya Reddy
Journal:  RSC Adv       Date:  2021-04-21       Impact factor: 3.361

3.  Influence of substituent modifications on the binding of 2-amino-1,8-naphthyridines to cytosine opposite an AP site in DNA duplexes: thermodynamic characterization.

Authors:  Yusuke Sato; Seiichi Nishizawa; Keitaro Yoshimoto; Takehiro Seino; Toshiki Ichihashi; Kotaro Morita; Norio Teramae
Journal:  Nucleic Acids Res       Date:  2009-01-09       Impact factor: 16.971
  3 in total

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