Literature DB >> 15916551

The herpes simplex virus ICP27 protein: a multifunctional post-transcriptional regulator of gene expression.

R W P Smith1, P Malik, J B Clements.   

Abstract

The herpes simplex virus 1 ICP27 is an essential, highly conserved protein involved in various steps of herpes simplex virus 1 gene regulation as well as in the shut-off of host gene expression during infection. It functions primarily at the post-transcriptional level in inhibiting precursor mRNA splicing and in promoting nuclear export of viral transcripts. These activities are discussed.

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Year:  2005        PMID： 15916551     DOI： 10.1042/BST0330499

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  21 in total

1.  Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene.

Authors:  Jennifer A Corcoran; Wei-Li Hsu; James R Smiley
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

2.  Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replication.

Authors:  C Salaun; A I MacDonald; O Larralde; L Howard; K Lochtie; H M Burgess; M Brook; P Malik; N K Gray; S V Graham
Journal:  J Virol       Date:  2010-06-23       Impact factor: 5.103

3.  Herpes Simplex Virus 1 Dramatically Alters Loading and Positioning of RNA Polymerase II on Host Genes Early in Infection.

Authors:  Claire H Birkenheuer; Charles G Danko; Joel D Baines
Journal:  J Virol       Date:  2018-03-28       Impact factor: 5.103

4.  Analysis of influenza B Virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains.

Authors:  Jana Schneider; Bianca Dauber; Krister Melén; Ilkka Julkunen; Thorsten Wolff
Journal:  J Virol       Date:  2008-11-05       Impact factor: 5.103

5.  Herpes simplex virus type 1 immediate-early protein ICP27 is required for efficient incorporation of ICP0 and ICP4 into virions.

Authors:  Lenka Sedlackova; Stephen A Rice
Journal:  J Virol       Date:  2007-10-24       Impact factor: 5.103

6.  ICP27 interacts with the C-terminal domain of RNA polymerase II and facilitates its recruitment to herpes simplex virus 1 transcription sites, where it undergoes proteasomal degradation during infection.

Authors:  Jenny Q Dai-Ju; Ling Li; Lisa A Johnson; Rozanne M Sandri-Goldin
Journal:  J Virol       Date:  2006-04       Impact factor: 5.103

7.  Extreme dependence of gH and gL expression on ORF57 and association with highly unusual codon usage in rhesus monkey rhadinovirus.

Authors:  John P Bilello; Jennifer S Morgan; Ronald C Desrosiers
Journal:  J Virol       Date:  2008-05-14       Impact factor: 5.103

8.  Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap binding.

Authors:  Richard W P Smith; Ross C Anderson; Osmany Larralde; Joel W S Smith; Barbara Gorgoni; William A Richardson; Poonam Malik; Sheila V Graham; Nicola K Gray
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-30       Impact factor: 11.205

9.  Direct stimulation of translation by the multifunctional herpesvirus ICP27 protein.

Authors:  Osmany Larralde; Richard W P Smith; Gavin S Wilkie; Poonam Malik; Nicola K Gray; J Barklie Clements
Journal:  J Virol       Date:  2006-02       Impact factor: 5.103

10.  Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways.

Authors:  Poonam Malik; Alijan Tabarraei; Ralph H Kehlenbach; Nadia Korfali; Ryota Iwasawa; Sheila V Graham; Eric C Schirmer
Journal:  J Biol Chem       Date:  2012-02-14       Impact factor: 5.157
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