| Literature DB >> 15913615 |
Stanley Juan C Gutierrez1, Fladmir de S Claudino, Bagnólia A Da Silva, Celso A Câmara, Reinaldo N de Almeida, Maria de Fátima V de Souza, Marcelo S Da Silva, Emídio V L Da-Cunha, José Maria Barbosa-Filho.
Abstract
A series of derivatives analogous to Nb-benzoyltryptamine were synthesized by the Schotten-Bauman procedure. The products obtained were: Nb-4-methoxy-benzoyltryptamine, Nb-2,4-dimethoxy-benzoyltryptamine, Nb-3,4-dimethoxy-benzoyltryptamine, Nb-3,4-methylenedioxy-benzoyltryptamine and Nb-3,4,5-trimethoxy-benzoyltryptamine. They were characterized through the usual spectrometric methods (UV, IR, 1H and 13C NMR) and showed non-selective relaxant activity in guinea-pig ileum pre-contracted with acetylcholine, histamine and KCl.Entities:
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Year: 2005 PMID： 15913615 DOI： 10.1016/j.farmac.2005.04.001
Source DB: PubMed Journal: Farmaco ISSN： 0014-827X