Literature DB >> 15911815

Evaluation of urinary PrPSc as a diagnostic test for sporadic, variant, and familial CJD.

M W Head1, E Kouverianou, L Taylor, A Green, R Knight.   

Abstract

Previously collected urine specimens from 100 patients referred to the UK National CJD Surveillance Unit as suspected cases of Creutzfeldt-Jakob disease (CJD) were analyzed, testing for abnormal prion protein (PrP(Sc)). In this context, the test had a low sensitivity and was not completely specific for CJD. Additionally, the proteins detected by this assay were not PrP(Sc) but appeared to be immunoglobulins.

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Year:  2005        PMID： 15911815     DOI： 10.1212/01.WNL.0000161842.68793.8A

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  10 in total

1.  Characterization of the prion protein in human urine.

Authors:  Ayuna Dagdanova; Serguei Ilchenko; Silvio Notari; Qiwei Yang; Mark E Obrenovich; Kristen Hatcher; Peter McAnulty; Lequn Huang; Wenquan Zou; Qingzhong Kong; Pierluigi Gambetti; Shu G Chen
Journal:  J Biol Chem       Date:  2010-07-29       Impact factor: 5.157

2.  Transmission and detection of prions in feces.

Authors:  Jiri G Safar; Pierre Lessard; Gültekin Tamgüney; Yevgeniy Freyman; Camille Deering; Frederic Letessier; Stephen J Dearmond; Stanley B Prusiner
Journal:  J Infect Dis       Date:  2008-07-01       Impact factor: 5.226

3.  Persistence of pathogenic prion protein during simulated wastewater treatment processes.

Authors:  Glen T Hinckley; Christopher J Johnson; Kurt H Jacobson; Christian Bartholomay; Katherine D McMahon; Debbie McKenzie; Judd M Aiken; Joel A Pedersen
Journal:  Environ Sci Technol       Date:  2008-07-15       Impact factor: 9.028

Review 4.  Clinical Use of Improved Diagnostic Testing for Detection of Prion Disease.

Authors:  Mark P Figgie; Brian S Appleby
Journal:  Viruses       Date:  2021-04-28       Impact factor: 5.048

5.  Assessing prion infectivity of human urine in sporadic Creutzfeldt-Jakob disease.

Authors:  Silvio Notari; Liuting Qing; Maurizio Pocchiari; Ayuna Dagdanova; Kristin Hatcher; Arend Dogterom; Jose F Groisman; Ib Bo Lumholtz; Maria Puopolo; Corinne Lasmezas; Shu G Chen; Qingzhong Kong; Pierluigi Gambetti
Journal:  Emerg Infect Dis       Date:  2012-01       Impact factor: 6.883

6.  Related or not? Development of spontaneous Creutzfeldt-Jakob disease in a patient with chronic, well-controlled HIV: A case report and review of the literature.

Authors:  M-Alain Babi; Bryan D Kraft; Sweta Sengupta; Haley Peterson; Ryan Orgel; Zachary Wegermann; Njira L Lugogo; Matthew W Luedke
Journal:  SAGE Open Med Case Rep       Date:  2016-10-13

7.  Ultra-efficient Amplification of Abnormal Prion Protein by Modified Protein Misfolding Cyclic Amplification with Electric Current.

Authors:  Jeong-Ho Park; Yeong-Gon Choi; Seok-Joo Park; Hong-Seok Choi; Eun-Kyoung Choi; Yong-Sun Kim
Journal:  Mol Neurobiol       Date:  2017-02-13       Impact factor: 5.590

8.  Excretion of transmissible spongiform encephalopathy infectivity in urine.

Authors:  Luisa Gregori; Gabor G Kovacs; Irina Alexeeva; Herbert Budka; Robert G Rohwer
Journal:  Emerg Infect Dis       Date:  2008-09       Impact factor: 6.883

Review 9.  Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases.

Authors:  Hasier Eraña; Jorge M Charco; Ezequiel González-Miranda; Sandra García-Martínez; Rafael López-Moreno; Miguel A Pérez-Castro; Carlos M Díaz-Domínguez; Adrián García-Salvador; Joaquín Castilla
Journal:  Biomolecules       Date:  2020-03-19

Review 10.  PMCA Applications for Prion Detection in Peripheral Tissues of Patients with Variant Creutzfeldt-Jakob Disease.

Authors:  Giorgio Giaccone; Fabio Moda
Journal:  Biomolecules       Date:  2020-03-05
  10 in total

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