| Literature DB >> 15909913 |
P V Mardanov, A N Krasnov, m M Kurshakova, E N Nabirochkina, S G Georgieva.
Abstract
It has been established that retrogenes lose introns and regulatory regions. Most of them become pseudogenes, but some acquire tissue-specific functions. In this study, a contrary situation is described, when a retrogene from Drosophila melanogaster performs the main functions and is expressed in all tissues, while the initial gene is active only in a small part of the male germ cells. It is suggested that this phenomenon resulted from retroposition of the initial precursor gene in the transcription-suitable region of the genome.Entities:
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Year: 2005 PMID: 15909913
Source DB: PubMed Journal: Genetika ISSN: 0016-6758