Literature DB >> 1590964

Complications of intrathecal baclofen delivery.

P Teddy1, A Jamous, B Gardner, D Wang, J Silver.   

Abstract

The medical records of 46 consecutive patients who have had intrathecal Baclofen drug delivery systems implanted in the National Spinal Injuries Centre, the Paddocks Hospital Spinal Unit, Princes Risborough, Lodge Moor Hospital Spinal Unit, Sheffield, the Northern Regional Spinal Injuries Unit, Hexham and The Radcliffe Infirmary, Oxford, were reviewed. Patients were contacted to describe their views on the treatment. The complications of the treatment are described. Some, such as overdose and meningitis are particularly hazardous. Others, in particular pump tubing revisions, are more of an inconvenience and time consuming for the patient and physician. If the serious risks of this valuable treatment are to be minimized and the therapy applied most effectively than a well co-ordinated team is essential, involving in particular the physician responsible for the initial assessment and follow-up of the patient and an experienced surgeon. It is recommended that only a small number of centres in the UK undertake these implants.

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Year:  1992        PMID: 1590964     DOI: 10.3109/02688699209002912

Source DB:  PubMed          Journal:  Br J Neurosurg        ISSN: 0268-8697            Impact factor:   1.596


  7 in total

1.  Cost analysis of the treatment of severe spinal spasticity with a continuous intrathecal baclofen infusion system.

Authors:  T J Postma; D Oenema; S Terpstra; J Bouma; H Kuipers-Upmeijer; M J Staal; B J Middel
Journal:  Pharmacoeconomics       Date:  1999-04       Impact factor: 4.981

2.  Intrathecal baclofen pump infection treated by adjunct intrareservoir antibiotic instillation.

Authors:  M Samuel; G T Finnerty; P Rudge
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-09       Impact factor: 10.154

3.  Effect of intrathecal baclofen delivered by an implanted programmable pump on health related quality of life in patients with severe spasticity.

Authors:  B Middel; H Kuipers-Upmeijer; J Bouma; M Staal; D Oenema; T Postma; S Terpstra; R Stewart
Journal:  J Neurol Neurosurg Psychiatry       Date:  1997-08       Impact factor: 10.154

4.  [Neurological complications and loss of efficacy with intrathecal pain therapy].

Authors:  D Kindler; C Maier; T Kagel; S Schulz; T Weiss; M Zenz
Journal:  Schmerz       Date:  2005-04       Impact factor: 1.107

5.  Intrathecal baclofen pump infection treated by adjunct intrareservoir teicoplanin instillation.

Authors:  Rovlias Aristedis; Papoutsakis Dimitrios; Paidakakos Nikolaos; Blionas Alexandros
Journal:  Surg Neurol Int       Date:  2017-03-14

6.  Intrathecal baclofen: Its effect on symptoms and activities of daily living in severe spasticity due to spinal cord injuries: A pilot study.

Authors:  Yogendrasinh Jagatsinh
Journal:  Indian J Orthop       Date:  2009-01       Impact factor: 1.251

Review 7.  Implantable Drug Delivery Systems and Foreign Body Reaction: Traversing the Current Clinical Landscape.

Authors:  Alexey Fayzullin; Alesia Bakulina; Karen Mikaelyan; Anatoly Shekhter; Anna Guller
Journal:  Bioengineering (Basel)       Date:  2021-12-09
  7 in total

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