| Literature DB >> 15908236 |
L Gullahorn1, L Lippiello, R Karpman.
Abstract
Anecdotal suggestions and retrospective studies indicate an inverse relationship between the incidence of osteoarthritis and individuals who smoke. As a possible explanation, our studies confirm that nicotine upregulates glycosaminoglycan and collagen synthetic activity of articular chondrocytes at physiological levels seen in individuals who smoke.Entities:
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Year: 2005 PMID: 15908236 DOI: 10.1016/j.joca.2005.03.001
Source DB: PubMed Journal: Osteoarthritis Cartilage ISSN: 1063-4584 Impact factor: 6.576