Literature DB >> 15908150

In vitro bioactivity-guided fractionation and characterization of polyphenolic inhibitory fractions from Acacia nilotica (L.) Willd. ex Del.

Kamaljit Kaur1, Husheem Michael, Saroj Arora, Pirkko Härkönen, Subodh Kumar.   

Abstract

The present study was undertaken to evaluate antimutagenic and cytotoxic effects of different extracts/fractions of Acacia nilotica prepared by maceration method. The potency order of different extracts was more or less similar in Ames assay as well as in cytotoxic assay. Considering the maximum potential of acetone extract in both the assays, the studies were initiated to fractionate this extract. Two pure fractions, namely AN-1 and AN-2, were obtained from acetone extract, of which AN-2 was found to be of gallic acid and AN-1 fraction is still to be identified. In conclusion, the antimutagenic and cytotoxic activities exhibited by acetone extract may partially be ascribed to the presence of gallic acid and other polyphenols.

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Year:  2005        PMID： 15908150     DOI： 10.1016/j.jep.2005.01.040

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  9 in total

1.  Metabolomic profiling and antioxidant activity of some Acacia species.

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2.  Isolation, characterization and biological activities of betulin from Acacia nilotica bark.

Authors:  Prabhjit Kaur; Saroj Arora; Rajbir Singh
Journal:  Sci Rep       Date:  2022-06-07       Impact factor: 4.996

3.  A unifying review of bioassay-guided fractionation, effect-directed analysis and related techniques.

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Journal:  Sensors (Basel)       Date:  2012-07-04       Impact factor: 3.576

4.  Free Radical Scavenging, Cytotoxic and Hemolytic Activities from Leaves of Acacia nilotica (L.) Wild. ex. Delile subsp. indica (Benth.) Brenan.

Authors:  T Kalaivani; C Rajasekaran; K Suthindhiran; Lazar Mathew
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-15       Impact factor: 2.629

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Authors:  Shashank Kumar; Abhay K Pandey
Journal:  BMC Complement Altern Med       Date:  2014-03-28       Impact factor: 3.659

Review 6.  The Effects of Tannins in Monogastric Animals with Special Reference to Alternative Feed Ingredients.

Authors:  Zahra Mohammed Hassan; Tlou Grace Manyelo; Letlhogonolo Selaledi; Monnye Mabelebele
Journal:  Molecules       Date:  2020-10-14       Impact factor: 4.411

7.  In vitro activities of Acacia nilotica (L.) Delile bark fractions against Oral Bacteria, Glucosyltransferase and as antioxidant.

Authors:  Ali Mahmoud Muddathir; Ebtihal Abdalla M Mohieldin; Tohru Mitsunaga
Journal:  BMC Complement Med Ther       Date:  2020-11-23

8.  Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways.

Authors:  Muhammad Imran Khan; Muhammad Zubair Khan; Jin Hyuk Shin; Tia Sun Shin; Young Bok Lee; Min Yung Kim; Jong Deog Kim
Journal:  Biomed Res Int       Date:  2021-11-12       Impact factor: 3.411

Review 9.  Herbal Drugs from Sudan: Traditional Uses and Phytoconstituents.

Authors:  Mohamed Gamaleldin Elsadig Karar; Nikolai Kuhnert
Journal:  Pharmacogn Rev       Date:  2017 Jul-Dec
  9 in total

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