Literature DB >> 1590727

The staggerer gene curtails the reproductive life span of females.

J M Guastavino1, K Larsson.   

Abstract

Three studies were undertaken to investigate some features of the reproductive activity of female staggerer mice of the C57BL/6 strain. It was found that in the staggerer female, (1) vaginal opening and onset of vaginal estrous cycling were delayed; (2) the vaginal estrous cycle was irregular and characterized by abnormally prolonged diestrous and estrous phases, and (3) the reproductive life span of the mutant female was confined to a 3-month period after puberty. The abnormalities observed in sexual functions suggest a specific influence of the staggerer gene on reproductive activity.

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Year:  1992        PMID： 1590727     DOI： 10.1007/bf01066795

Source DB:  PubMed          Journal:  Behav Genet        ISSN： 0001-8244            Impact factor:   2.805


  26 in total

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Authors:  R L SIDMAN; P W LANE; M M DICKIE
Journal:  Science       Date:  1962-08-24       Impact factor: 47.728

2.  Purkinje cell degeneration, a new neurological mutation in the mouse.

Authors:  R J Mullen; E M Eicher; R L Sidman
Journal:  Proc Natl Acad Sci U S A       Date:  1976-01       Impact factor: 11.205

Review 3.  The cerebellum and learning processes in animals.

Authors:  R Lalonde; M I Botez
Journal:  Brain Res Brain Res Rev       Date:  1990 Sep-Dec

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Authors:  R Misslin; M Cigrang; J M Guastavino
Journal:  Behav Processes       Date:  1986-01       Impact factor: 1.777

5.  Transsynaptic degeneration 'en cascade' in the cerebellar cortex of staggerer mutant mice.

Authors:  C Sotelo; J P Changeux
Journal:  Brain Res       Date:  1974-03-08       Impact factor: 3.252

6.  Hypothalamo-cerebellar and cerebello-hypothalamic pathways: a review and hypothesis concerning cerebellar circuits which may influence autonomic centers affective behavior.

Authors:  D E Haines; E Dietrichs; T E Sowa
Journal:  Brain Behav Evol       Date:  1984       Impact factor: 1.808

7.  Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the adult staggerer mutant mouse.

Authors:  J Mariani; J P Changeux
Journal:  J Neurobiol       Date:  1980

8.  Daily administration of melatonin delays rat vaginal opening and disrupts the first estrous cycles: evidence that these effects are synchronized by the onset of light.

Authors:  R W Rivest; U Lang; M L Aubert; P C Sizonenko
Journal:  Endocrinology       Date:  1985-02       Impact factor: 4.736

9.  Effects of cold acclimation on the energetic metabolism of the staggerer mutant mouse.

Authors:  R Bertin; J M Guastavino; R Portet
Journal:  Physiol Behav       Date:  1990-02

10.  Degeneration of thalamic neurons in "Purkinje cell degeneration" mutant mice. I. Distribution of neuron loss.

Authors:  S O'Gorman; R L Sidman
Journal:  J Comp Neurol       Date:  1985-04-15       Impact factor: 3.215
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  6 in total

1.  In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism.

Authors:  T Meyer; M Kneissel; J Mariani; B Fournier
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

2.  Neonatal vestibular stimulation and mating in cerebellar mutants.

Authors:  J M Guastavino; K Larsson; C Allain; P Jaisson
Journal:  Behav Genet       Date:  1993-05       Impact factor: 2.805

3.  Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV.

Authors:  C D Kane; A R Means
Journal:  EMBO J       Date:  2000-02-15       Impact factor: 11.598

4.  Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival.

Authors:  Sonja Janmaat; Yvette Akwa; Mohamed Doulazmi; Joëlle Bakouche; Vanessa Gautheron; Philippe Liere; Bernard Eychenne; Antoine Pianos; Paul Luiten; Ton Groothuis; Etienne-Emile Baulieu; Jean Mariani; Rachel M Sherrard; Florence Frédéric
Journal:  Age (Dordr)       Date:  2011-01-11

5.  Genome-wide association and identification of candidate genes for age at puberty in swine.

Authors:  Dan J Nonneman; James F Schneider; Clay A Lents; Ralph T Wiedmann; Jeffrey L Vallet; Gary A Rohrer
Journal:  BMC Genet       Date:  2016-02-29       Impact factor: 2.797

6.  Endocrine and molecular factors of increased female reproductive performance in the Dummerstorf high-fertility mouse line FL1.

Authors:  Carolin Lisa Michaela Ludwig; Simon Bohleber; Alexander Rebl; Eva Katrin Wirth; Marzia Tindara Venuto; Martina Langhammer; Ulrich Schweizer; Joachim M Weitzel; Marten Michaelis
Journal:  J Mol Endocrinol       Date:  2022-05-17       Impact factor: 4.869
  6 in total

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