Literature DB >> 15906369

Apoptotic and anti-angiogenic strategies in liver and gastrointestinal malignancies.

Jannis Kountouras1, Christos Zavos, Dimitrios Chatzopoulos.   

Abstract

Inappropriate suppression of apoptosis is strongly implicated in tumorigenesis. Tumor development is heralded by the mutation of tumor suppressor genes and overexpression of anti-apoptotic genes permitting cell survival. Thus, inducing the apoptotic process in various ways can be applied to cancer management. Besides, angiogenesis is a crucial process for tumor growth and metastasis. New strategies targeting fundamental play-markers of the angiogenic process are currently under investigation.

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Year:  2005        PMID： 15906369     DOI： 10.1002/jso.20254

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  6 in total

1.  The prognostic significance of p53 expression in gastric cancer: a meta-analysis.

Authors:  Kongkong Wei; Lei Jiang; Yaoyao Wei; Yufeng Wang; Xuankun Qian; Qiang Dai; Quanlin Guan
Journal:  J Cancer Res Clin Oncol       Date:  2014-10-15       Impact factor: 4.553

2.  Induction of apoptosis of human colon cancer cells by siRNA recombinant expression vector targeting survivin gene.

Authors:  Ming Cai; Guobin Wang; Kaixiong Tao; Changxue Cai
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2009-02-18

3.  Down-regulation of survivin suppresses uro-plasminogen activator through transcription factor JunB.

Authors:  Kyung Hee Lee; Eun Young Choi; Sung Ae Koh; Min Kyoung Kim; Kyeong Ok Kim; Si Hyung Lee; Byung Ik Jang; Se Won Kim; Sang Woon Kim; Sun Kyo Song; Joon Hyuk Choi; Jae-Ryong Kim
Journal:  Exp Mol Med       Date:  2011-09-30       Impact factor: 8.718

4.  COX-2 is associated with proliferation and apoptosis markers and serves as an independent prognostic factor in gastric cancer.

Authors:  Johanna Mrena; Jan-Patrik Wiksten; Arto Kokkola; Stig Nordling; Ari Ristimäki; Caj Haglund
Journal:  Tumour Biol       Date:  2009-12-18

Review 5.  Cruciferous vegetables as a treasure of functional foods bioactive compounds: Targeting p53 family in gastrointestinal tract and associated cancers.

Authors:  Saikat Mitra; Talha Bin Emran; Deepak Chandran; B M Redwan Matin Zidan; Rajib Das; Sukamto S Mamada; Ayu Masyita; Mirnawati Salampe; Firzan Nainu; Mayeen Uddin Khandaker; Abubakr M Idris; Jesus Simal-Gandara
Journal:  Front Nutr       Date:  2022-08-04

6.  Expression and Functional Analysis of Storage Protein 2 in the Silkworm, Bombyx mori.

Authors:  Wei Yu; Meihui Wang; Hanming Zhang; Yanping Quan; Yaozhou Zhang
Journal:  Int J Genomics       Date:  2013-03-26       Impact factor: 2.326
  6 in total

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