Literature DB >> 15905465

Signaling of the tissue factor coagulation pathway in angiogenesis and cancer.

Mattias Belting1, Jasimuddin Ahamed, Wolfram Ruf.   

Abstract

Activation of coagulation precedes or coincides with angiogenesis in wound healing and postischemic tissue regeneration. Advanced cancer is associated with a hypercoagulable state, and tissue factor expression by cancer cells has received widespread attention because of its significant contribution to the pathogenesis of cancer progression and metastasis. Our recent work demonstrates that tissue factor-mediated cellular signaling is relevant to cancer angiogenesis. Here we review the molecular mechanisms of tissue factor pathways in angiogenesis and tumorigenesis with emphasis on the intriguing role for tissue factor cytoplasmic domain signaling.

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Year:  2005        PMID: 15905465     DOI: 10.1161/01.ATV.0000171155.05809.bf

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN: 1079-5642            Impact factor:   8.311


  61 in total

Review 1.  Tissue factor and PAR2 signaling in the tumor microenvironment.

Authors:  Florence Schaffner; Wolfram Ruf
Journal:  Arterioscler Thromb Vasc Biol       Date:  2009-08-06       Impact factor: 8.311

2.  Antithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade.

Authors:  Rômulo A Nazareth; Luana S Tomaz; Susana Ortiz-Costa; Geórgia C Atella; José M C Ribeiro; Ivo M B Francischetti; Robson Q Monteiro
Journal:  Thromb Haemost       Date:  2006-07       Impact factor: 5.249

3.  Tissue factor in cancer progression and angiogenesis.

Authors:  Wolfram Ruf; Naho Yokota; Florence Schaffner
Journal:  Thromb Res       Date:  2010-04       Impact factor: 3.944

4.  The pro-migratory and pro-invasive role of the procoagulant tissue factor in malignant gliomas.

Authors:  Stephan Dützmann; Florian Gessler; Patrick N Harter; Rüdiger Gerlach; Michel Mittelbronn; Volker Seifert; Donat Kögel
Journal:  Cell Adh Migr       Date:  2010 Oct-Dec       Impact factor: 3.405

Review 5.  Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations.

Authors:  Balazs I Bodai; Phillip Tuso
Journal:  Perm J       Date:  2015

6.  Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis.

Authors:  Chloe C Milsom; Joanne L Yu; Nigel Mackman; Johann Micallef; G Mark Anderson; Abhijit Guha; Janusz W Rak
Journal:  Cancer Res       Date:  2008-12-15       Impact factor: 12.701

7.  Transcriptional program induced by factor VIIa-tissue factor, PAR1 and PAR2 in MDA-MB-231 cells.

Authors:  T Albrektsen; B B Sørensen; G M Hjortø; J Fleckner; L V M Rao; L C Petersen
Journal:  J Thromb Haemost       Date:  2007-04-27       Impact factor: 5.824

8.  Thioredoxin and thioredoxin reductase control tissue factor activity by thiol redox-dependent mechanism.

Authors:  Pei Wang; Yunfei Wu; Xiaoming Li; Xiaofeng Ma; Liangwei Zhong
Journal:  J Biol Chem       Date:  2012-12-07       Impact factor: 5.157

9.  Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model.

Authors:  T C Carneiro-Lobo; S Konig; D E Machado; L E Nasciutti; M F Forni; I M B Francischetti; M C Sogayar; R Q Monteiro
Journal:  J Thromb Haemost       Date:  2009-07-17       Impact factor: 5.824

Review 10.  Role of tissue factor disulfides and lipid rafts in signaling.

Authors:  Usha R Pendurthi; L Vijaya Mohan Rao
Journal:  Thromb Res       Date:  2008       Impact factor: 3.944

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