Literature DB >> 15901376

Soft tissue sarcomas: are current referral guidelines sufficient?

R Hussein1, M A Smith.   

Abstract

INTRODUCTION: To investigate the adequacy of current early referral guidelines for patients with extremity soft tissue sarcomas. PATIENTS &
METHODS: 365 patients with confirmed soft tissue sarcomas were evaluated. Data were collected prospectively and included the length of history and the presence of features in current guidelines suggestive of malignancy (pain, rapidity of growth, depth and tumour size). Statistical analysis included the t-test, ANOVA and the Chi test.
RESULTS: Deep tumours were the commonest (306 patients with deep tumours). Pain was the least consistent feature (176 patients with pain). 345 patients with one or more of the guideline features had an average history of 19.86 months, 238 of these were seen after more than 3 months.
CONCLUSION: Although the majority of soft tissue sarcomas in our patients had one or more of the clinical guideline features, there was still an unacceptable delay in referring these patients to a specialist unit. The referral guidelines should be modified with special emphasis on depth, which is the most sensitive, followed by size and a history of rapid growth. This combined with increased awareness of these guidelines and a well-advertised, open-access clinic linked to a specialist unit should allow for a more rapid evaluation of soft tissue tumours.

Entities:  

Mesh:

Year:  2005        PMID: 15901376      PMCID: PMC1963892          DOI: 10.1308/1478708051658

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  19 in total

1.  Trends in presentation of bone and soft tissue sarcomas over 25 years: little evidence of earlier diagnosis.

Authors:  G M Smith; G D Johnson; R J Grimer; S Wilson
Journal:  Ann R Coll Surg Engl       Date:  2011-10       Impact factor: 1.891

Review 2.  Ultrasound evaluation of superficial lumps and bumps of the extremities in children: a 5-year retrospective review.

Authors:  Samir H Shah; Michael J Callahan
Journal:  Pediatr Radiol       Date:  2013-03-12

3.  Does the two-week rule pathway improve the diagnosis of soft tissue sarcoma? A retrospective review of referral patterns and outcomes over five years in a regional sarcoma centre.

Authors:  Tim D Pencavel; Dirk C Strauss; Greg P Thomas; J Meirion Thomas; Andrew J Hayes
Journal:  Ann R Coll Surg Engl       Date:  2010-05-19       Impact factor: 1.891

4.  Retrospective analysis of the impact of symptom duration on prognosis in soft tissue sarcoma.

Authors:  A Saithna; P B Pynsent; R J Grimer
Journal:  Int Orthop       Date:  2007-03-22       Impact factor: 3.075

5.  Conformity to Clinical Practice Guidelines at Initial Management in Adult Soft Tissue and Visceral Tumors since the Implementation of the NetSarc Network in Eastern France.

Authors:  Justine Gantzer; Antonio Di Marco; Thibaut Fabacher; Noelle Weingertner; Jean-Baptiste Delhorme; David Brinkert; Guillaume Bierry; Jean-Pierre Ghnassia; Jérémie Jégu; Jean-Emmanuel Kurtz
Journal:  Oncologist       Date:  2019-05-09

6.  MRI to differentiate benign from malignant soft-tissue tumours of the extremities: a simplified systematic imaging approach using depth, size and heterogeneity of signal intensity.

Authors:  W J Chung; H W Chung; M J Shin; S H Lee; M H Lee; J S Lee; M-J Kim; W K Lee
Journal:  Br J Radiol       Date:  2012-05-02       Impact factor: 3.039

7.  Perfusion pattern of musculoskeletal masses using contrast-enhanced ultrasound: a helpful tool for characterisation?

Authors:  Alexander Loizides; Siegfried Peer; Michaela Plaikner; Tanja Djurdjevic; Hannes Gruber
Journal:  Eur Radiol       Date:  2012-03-13       Impact factor: 5.315

8.  Adherence to consensus-based diagnosis and treatment guidelines in adult soft-tissue sarcoma patients: a French prospective population-based study.

Authors:  S Mathoulin-Pélissier; C Chevreau; C Bellera; E Bauvin; M Savès; P Grosclaude; S Albert; J Goddard; S Le Guellec; M Delannes; B N Bui; J Mendiboure; E Stoeckle; J M Coindre; G Kantor; M Kind; A Cowppli-Bony; S Hoppe; A Italiano
Journal:  Ann Oncol       Date:  2013-11-26       Impact factor: 32.976

Review 9.  Centralised treatment of soft tissue sarcomas in adults.

Authors:  Luis A Pérez Romasanta; Angel Montero Luis; Ramona Verges Capdevila; Alfonso Mariño Cotelo; José M Rico Pérez
Journal:  Clin Transl Oncol       Date:  2008-02       Impact factor: 3.405

10.  Assessment of referrals into the soft tissue sarcoma service: evaluation of imaging early in the pathway process.

Authors:  Emma Rowbotham; Shaheel Bhuva; Harun Gupta; Philip Robinson
Journal:  Sarcoma       Date:  2012-06-26
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