Literature DB >> 15901177

Mycapolyols A-F, new cytotoxic metabolites of mixed biogenesis from the marine sponge Mycale izuensis.

Preecha Phuwapraisirisan1, Shigeki Matsunaga, Nobuhiro Fusetani.   

Abstract

[structure: see text]. Mycapolyols A-F (1-6), six new unusual PKS/NRPS metabolites, were isolated from the marine sponge Mycale izuensis. The gross structures were elucidated by analysis of spectroscopic data, while the stereochemistry was established using chemical method and the universal NMR database.

Mesh:

Substances:

Year:  2005        PMID: 15901177     DOI: 10.1021/ol050648m

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  The screening of antimicrobial bacteria with diverse novel nonribosomal peptide synthetase (NRPS) genes from South China sea sponges.

Authors:  Wei Zhang; Zhiyong Li; Xiaoling Miao; Fengli Zhang
Journal:  Mar Biotechnol (NY)       Date:  2008-10-14       Impact factor: 3.619

2.  Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4.

Authors:  Tanja Grkovic; Johanna S Blees; Nancy H Colburn; Tobias Schmid; Cheryl L Thomas; Curtis J Henrich; James B McMahon; Kirk R Gustafson
Journal:  J Nat Prod       Date:  2011-05-03       Impact factor: 4.050

3.  Changes in bacterial communities of the marine sponge Mycale laxissima on transfer into aquaculture.

Authors:  Naglaa M Mohamed; Julie J Enticknap; Jayme E Lohr; Scott M McIntosh; Russell T Hill
Journal:  Appl Environ Microbiol       Date:  2007-12-21       Impact factor: 4.792

Review 4.  Marine pharmacology in 2005-2006: antitumour and cytotoxic compounds.

Authors:  Alejandro M S Mayer; Kirk R Gustafson
Journal:  Eur J Cancer       Date:  2008-08-11       Impact factor: 9.162

5.  Studies toward the Synthesis of Smenamide A, an Antiproliferative Metabolite from Smenospongia aurea: Total Synthesis of ent-Smenamide A and 16-epi-Smenamide A.

Authors:  Alessia Caso; Alfonso Mangoni; Gennaro Piccialli; Valeria Costantino; Vincenzo Piccialli
Journal:  ACS Omega       Date:  2017-04-17

Review 6.  Chemistry and Biological Activities of the Marine Sponges of the Genera Mycale (Arenochalina), Biemna and Clathria.

Authors:  Amr El-Demerdash; Mohamed A Tammam; Atanas G Atanasov; John N A Hooper; Ali Al-Mourabit; Anake Kijjoa
Journal:  Mar Drugs       Date:  2018-06-18       Impact factor: 5.118

7.  Smenamides A and B, chlorinated peptide/polyketide hybrids containing a dolapyrrolidinone unit from the Caribbean sponge Smenospongia aurea. Evaluation of their role as leads in antitumor drug research.

Authors:  Roberta Teta; Elena Irollo; Gerardo Della Sala; Giuseppe Pirozzi; Alfonso Mangoni; Valeria Costantino
Journal:  Mar Drugs       Date:  2013-11-08       Impact factor: 5.118

  7 in total

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