Literature DB >> 15900325

Biosynthesis of conjugatable saccharidic moieties of GM2 and GM3 gangliosides by engineered E. coli.

Sébastien Fort1, Lemonia Birikaki, Marie-Pierre Dubois, Tatiana Antoine, Eric Samain, Hugues Driguez.   

Abstract

Oligosaccharidic moieties of GM(2) and GM(3) gangliosides bearing an allyl or a propargyl aglycon, are efficiently biosynthesized on the gram scale by growing metabolically engineered Escherichia coli cells in the presence of the corresponding lactoside acceptors and sialic acid.

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Year:  2005        PMID: 15900325     DOI: 10.1039/b500686d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  Advances in the biology and chemistry of sialic acids.

Authors:  Xi Chen; Ajit Varki
Journal:  ACS Chem Biol       Date:  2010-02-19       Impact factor: 5.100

2.  Utilizing the O-antigen lipopolysaccharide biosynthesis pathway in Escherichia coli to interrogate the substrate specificities of exogenous glycosyltransferase genes in a combinatorial approach.

Authors:  Eric B Johansen; Francis C Szoka; Anthony Zaleski; Michael A Apicella; Bradford W Gibson
Journal:  Glycobiology       Date:  2010-03-05       Impact factor: 4.313

Review 3.  Sialic acid metabolism and sialyltransferases: natural functions and applications.

Authors:  Yanhong Li; Xi Chen
Journal:  Appl Microbiol Biotechnol       Date:  2012-04-13       Impact factor: 4.813

4.  Electrogenerated poly(pyrrole-lactosyl) and poly(pyrrole-3'-sialyllactosyl) interfaces: toward the impedimetric detection of lectins.

Authors:  Chantal Gondran; Marie-Pierre Dubois; Sébastien Fort; Serge Cosnier
Journal:  Front Chem       Date:  2013-07-12       Impact factor: 5.221

Review 5.  Ganglioside biochemistry.

Authors:  Thomas Kolter
Journal:  ISRN Biochem       Date:  2012-12-19

Review 6.  The sweet branch of metabolic engineering: cherry-picking the low-hanging sugary fruits.

Authors:  Rachel Chen
Journal:  Microb Cell Fact       Date:  2015-12-09       Impact factor: 5.328

7.  Misincorporation of Galactose by Chondroitin Synthase of Escherichia coli K4: From Traces to Synthesis of Chondbiuronan, a Novel Chondroitin-Like Polysaccharide.

Authors:  Mélanie Leroux; Julie Michaud; Eric Bayma; Sylvie Armand; Sophie Drouillard; Bernard Priem
Journal:  Biomolecules       Date:  2020-12-12
  7 in total

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