Literature DB >> 15900115

The utility of MIB-1/Ki-67 immunostaining in the evaluation of central nervous system neoplasms.

Richard A Prayson1.   

Abstract

The diagnosis and assignment of grade in neoplasms of the central nervous system (CNS), for the most part, are morphologically based and predicated on the interpretation of descriptions of what the phenotypic findings are for a particular tumor type. Not surprisingly, the application of various grading systems in CNS neoplasia has been limited somewhat by interobserver variability. Since assignment of grade and tumor type is the basis upon which therapeutic intervention is grounded, investigators have been searching for ancillary means by which morphologically based systems can be improved. Utilization of cell proliferation markers in the evaluation of tumors can be potentially useful in this endeavor. This review focuses on issues surrounding the utilization of MIB-1 or Ki-67 antibody in the evaluation of CNS neoplasms.

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Year:  2005        PMID： 15900115     DOI： 10.1097/01.pap.0000163957.21409.52

Source DB:  PubMed          Journal:  Adv Anat Pathol        ISSN： 1072-4109            Impact factor:   3.875


  17 in total

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Authors:  Tove Lind-Landström; Andreas Hanssøn Habberstad; Stein Sundstrøm; Sverre Helge Torp
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2.  Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice.

Authors:  Fanny Burel-Vandenbos; Laurent Turchi; Maxime Benchetrit; Eric Fontas; Zoe Pedeutour; Valérie Rigau; Fabien Almairac; Damien Ambrosetti; Jean-François Michiels; Thierry Virolle
Journal:  Neuro Oncol       Date:  2013-08-09       Impact factor: 12.300

3.  Aggressive Low-Grade Optic Nerve Glioma in Adults.

Authors:  Gorkem Bilgin; Majed Al-Obailan; Laura Bonelli; Ben J Glasgow; Harry V Vinters; Anthony C Arnold
Journal:  Neuroophthalmology       Date:  2014-11-12

4.  Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas.

Authors:  Elena Karavaeva; Robert J Harris; Kevin Leu; Maryam Shabihkhani; William H Yong; Whitney B Pope; Albert Lai; Phioanh L Nghiemphu; Linda M Liau; Wei Chen; Johannes Czernin; Timothy F Cloughesy; Benjamin M Ellingson
Journal:  Mol Imaging Biol       Date:  2015-06       Impact factor: 3.488

5.  Ki-67/MIB-1 immunostaining in a cohort of human gliomas.

Authors:  Anne J Skjulsvik; Jørgen N Mørk; Morten O Torp; Sverre H Torp
Journal:  Int J Clin Exp Pathol       Date:  2014-12-01

6.  (99m)Tc-Tetrofosmin brain SPECT in the assessment of meningiomas-correlation with histological grade and proliferation index.

Authors:  Andreas D Fotopoulos; George A Alexiou; Ann Goussia; Athanasios Papadopoulos; Athanasios P Kyritsis; Konstantinos S Polyzoidis; Spyridon Voulgaris; Spyridon Tsiouris
Journal:  J Neurooncol       Date:  2008-05-06       Impact factor: 4.130

7.  The Study of MIB-1 LI and CD 34 As A Marker of Proliferative Activity and Angiogenesis in Different Grades of Meningioma.

Authors:  Harishkumar Bohra; Khushi Ram Rathi; Sharmila Dudani; Ashish Bohra; Sumit Vishwakarma; Kavita Sahai
Journal:  J Clin Diagn Res       Date:  2016-08-01

8.  Implicating chromosomal aberrations with meningioma growth and recurrence: results from FISH and MIB-I analysis of grades I and II meningioma tissue.

Authors:  Wolfgang K Pfisterer; Stephen W Coons; Fahmy Aboul-Enein; William P Hendricks; Adrienne C Scheck; Mark C Preul
Journal:  J Neurooncol       Date:  2007-11-30       Impact factor: 4.130

9.  The value of positron emission tomography and proliferation index in predicting progression in low-grade astrocytomas of childhood.

Authors:  Michael C Kruer; Allen M Kaplan; Michael M Etzl; David F Carpentieri; Paul S Dickman; Kewei Chen; Kathleen Mathieson; Alison Irving
Journal:  J Neurooncol       Date:  2009-06-09       Impact factor: 4.130

10.  Accurate quantitation of Ki67-positive proliferating hepatocytes in rabbit liver by a multicolor immunohistochemical (IHC) approach analyzed with automated tissue and cell segmentation software.

Authors:  Chris M van der Loos; Onno J de Boer; Claire Mackaaij; Lisette T Hoekstra; Thomas M van Gulik; Joanne Verheij
Journal:  J Histochem Cytochem       Date:  2012-09-01       Impact factor: 2.479
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