Literature DB >> 15899620

[Malignant cardiac tumors].

Philippe Debourdeau1, Joseph Gligorov, Luis Teixeira, Marc Aletti, Christine Zammit.   

Abstract

Cardiac neoplasms are a rare occurrence in clinical practice. The various frequencies of primary and secondary malignant tumors vary from report to report, approximately 1% in most autopsy series and 4% in cancer patient's autopsies. Cardiac malignancies account for less 1% of cardiac surgery and about for 0.1% of cardiac echographic studies. The presence of metastatic tumor to the heart usually indicates widespread metastases. Lung carcinomas are the most commonly encountered tumor followed by breast and pancreas cancer and melanoma. Apart from primary pericardial mesothelioma, primary cardiac tumors are high-grade sarcomas with a high metastatic potency that often becomes evident early after surgery. Symptoms are non specific, occur late in the disease and affect few patients; especially secondary neoplasms of the heart take their course so fast that they cannot become symptomatic. The signs of cardiac neoplasms are divided into systemic symptoms (fever, arthralgias and myalgias), cardiac symptoms (congestive heart failure, arrhythmia, chest pain) and uncommon embolisms. Diagnosis is actually made easier with cardiac echography. Cardiac RMI is helpful to estimate vessels and pericardium involvement. Due to its poor prognosis, treatment of cardiac metastases is restricted to best supportive care. For primary cardiac neoplasms, surgery must be carefully discussed because operative intervention is often followed by rapid widespread metastases that adjuvant chemotherapy cannot avoid in most cases.

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Year:  2004        PMID: 15899620

Source DB:  PubMed          Journal:  Bull Cancer        ISSN: 0007-4551            Impact factor:   1.276


  4 in total

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Journal:  Ann Transl Med       Date:  2019-11

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Authors:  David Sladden; Kentaro Yamagata; Elton Pllaha; Walter Busuttil
Journal:  BMJ Case Rep       Date:  2015-06-21

3.  Clinical implication of surgical resection for the rare cardiac tumors involving heart and great vessels.

Authors:  Se Jin Oh; Sang Yoon Yeom; Kyung-Hwan Kim
Journal:  J Korean Med Sci       Date:  2013-05-02       Impact factor: 2.153

4.  Preoperative assessment of mitral valve abnormalities in left atrial myxoma patients using cardiac CT.

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Journal:  Oncotarget       Date:  2017-03-11
  4 in total

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