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Literature DB >> 15899388

Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma.

Ken M Gatter¹, Susan Olson, Helen Lawce, Anne E Rader.

Abstract

Mesenchymal chondrosarcoma is a rare malignant tumor that comprises about 3-10% of all sarcomas. Reports of cytogenetic studies of mesenchymal chondrosarcoma are limited and no consistent cytogenetic abnormality has surfaced. Some mesenchymal chondrosarcomas have a t(11;22) translocation suggesting a relationship with the PNET/Ewing tumor family. We report what to our knowledge is the first case of trisomy 8 as the sole cytogenetic abnormality in a mesenchymal chondrosarcoma.

Entities: Disease

Mesh：

Year: 2005 PMID： 15899388 DOI： 10.1016/j.cancergencyto.2004.10.007

Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608

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Cited

6 in total

1. Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma.

Authors: Shalini A Amukotuwa; Peter F M Choong; Peter J Smith; Gerard J Powell; David Thomas; Stephen M Schlicht
Journal: Skeletal Radiol Date: 2005-11-18 Impact factor: 2.199

2. A rare case of extraskeletal mesenchymal chondrosarcoma with dedifferentiation arising from the buccal space in a young male.

Authors: Shalini R Gupta; Ravinder K Saran; Pankaj Sharma; Aadithya B Urs
Journal: J Maxillofac Oral Surg Date: 2013-03-27

6. Primary spinal intradural mesenchymal chondrosarcoma with detection of fusion gene HEY1-NCOA2: A paediatric case report and review of the literature.

Authors: Carola Andersson; Gustaf Osterlundh; Fredrik Enlund; Lars-Gunnar Kindblom; Magnus Hansson
Journal: Oncol Lett Date: 2014-07-18 Impact factor: 2.967

6 in total

Trisomy 8 as the sole cytogenetic abnormality in a case of extraskeletal mesenchymal chondrosarcoma.

1. Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma.

2. A rare case of extraskeletal mesenchymal chondrosarcoma with dedifferentiation arising from the buccal space in a young male.

3. Retroperitoneal mesenchymal chondrosarcoma mimicking a large retroperitoneal sacral schwannoma.

4. Mesenchymal chondrosarcoma metastasising to the pancreas.

5. Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma.

6. Primary spinal intradural mesenchymal chondrosarcoma with detection of fusion gene HEY1-NCOA2: A paediatric case report and review of the literature.