Literature DB >> 1589762

Human gene therapy.

W F Anderson1.   

Abstract

Human gene therapy is a procedure that is being used in an attempt to treat genetic and other diseases. Eleven clinical protocols are under way at the present time, each with scientific and clinical objectives. Human genetic engineering raises unique safety, social, and ethical concerns.

Entities:  

Keywords:  Analytical Approach; Biomedical and Behavioral Research; Genetics and Reproduction; National Institutes of Health

Mesh：

Substances：

Year:  1992        PMID： 1589762     DOI： 10.1126/science.1589762

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  109 in total

Review 1.  Nonviral gene transfer strategies for the vasculature.

Authors:  Jennifer L Young; David A Dean
Journal:  Microcirculation       Date:  2002-01       Impact factor: 2.628

2.  In vivo retroviral gene transfer into human bronchial epithelia of xenografts.

Authors:  J F Engelhardt; J R Yankaskas; J M Wilson
Journal:  J Clin Invest       Date:  1992-12       Impact factor: 14.808

Review 3.  Gene therapy.

Authors:  S M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

4.  [Molecular biology in the intensive care unit--or: genes and destiny].

Authors:  M Bauer
Journal:  Anaesthesist       Date:  2004-03       Impact factor: 1.041

5.  Gene therapy.

Authors:  B Williamson
Journal:  Gut       Date:  1992-12       Impact factor: 23.059

Review 6.  Gene therapy in clinical medicine.

Authors:  S M Selkirk
Journal:  Postgrad Med J       Date:  2004-10       Impact factor: 2.401

7.  Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses.

Authors:  J S Remy; A Kichler; V Mordvinov; F Schuber; J P Behr
Journal:  Proc Natl Acad Sci U S A       Date:  1995-02-28       Impact factor: 11.205

8.  Efficient gene transfer into human hepatocytes by baculovirus vectors.

Authors:  C Hofmann; V Sandig; G Jennings; M Rudolph; P Schlag; M Strauss
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205

9.  Retrovirus infection: effect of time and target cell number.

Authors:  J R Morgan; J M LeDoux; R G Snow; R G Tompkins; M L Yarmush
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

10.  Negative effects of wild-type p53 and s-Myc on cellular growth and tumorigenicity of glioma cells. Implication of the tumor suppressor genes for gene therapy.

Authors:  A Asai; Y Miyagi; A Sugiyama; M Gamanuma; S H Hong; S Takamoto; K Nomura; M Matsutani; K Takakura; Y Kuchino
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130
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