| Literature DB >> 15896957 |
Miho Katoh1, Kosuke Dodo, Mikako Fujita, Mikiko Sodeoka.
Abstract
A series of N-methyl-bisindolylmaleimide derivatives was synthesized and evaluated as cell death inhibitors. N-Methyl-2-[1-(3-aminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide (21) was the most potent inhibitor of H2O2-induced necrotic death of human leukemia HL60 cells among them.Entities:
Mesh：
Substances：
Year: 2005 PMID： 15896957 DOI： 10.1016/j.bmcl.2005.04.015
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823