| Literature DB >> 15896452 |
Annelyse Duvoix1, Romain Blasius, Sylvie Delhalle, Michaël Schnekenburger, Franck Morceau, Estelle Henry, Mario Dicato, Marc Diederich.
Abstract
Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems. In this review, we describe both properties and mode of action of curcumin on carcinogenesis, gene expression mechanisms and drug metabolism.Entities:
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Year: 2004 PMID： 15896452 DOI： 10.1016/j.canlet.2004.09.041
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679