Literature DB >> 15896374

Marsdenosides A-H, polyoxypregnane glycosides from Marsdenia tenacissima.

Jun Deng1, Zhixin Liao, Daofeng Chen.   

Abstract

Eight polyoxypregnane glycosides, marsdenosides A-H, were isolated from the CHCl(3)-soluble fraction of the ethanolic extract of the stem of Marsdenia tenacissima, along with six known glycosides and two known polyoxypregnane aglycones. Three polyoxypregnanes, 12beta-O-2-methylbutyryl-tenacigenin A, 11alpha,12beta-di-O-acetyltenacigenin B, and 11alpha-O-tigloyltenacigenin B were also obtained. Their structures were established on the basis of spectroscopic analysis and chemical evidence.

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Year:  2005        PMID: 15896374     DOI: 10.1016/j.phytochem.2005.03.018

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  8 in total

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Journal:  J Nat Med       Date:  2014-08-21       Impact factor: 2.343

2.  C21 steroid derivatives from the Dai herbal medicine Dai-Bai-Jie, the dried roots of Marsdenia tenacissima, and their screening for anti-HIV activity.

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3.  The cytotoxic and tyrosine kinase inhibitory properties of C21 steroids and iridoids from the tubers of Alocasia cucullata.

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Journal:  Pharmacogn Mag       Date:  2014-08       Impact factor: 1.085

5.  Integrated approach for identifying and evaluating the quality of Marsdenia tenacissima in the medicine market.

Authors:  Ning Yu; Yu-Long Wei; Yue Zhu; Ning Zhu; Yan-Li Wang; Hai-Ping Zhang; Ai-Dong Sun
Journal:  PLoS One       Date:  2018-04-06       Impact factor: 3.240

6.  C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways.

Authors:  Yu Zhang; Kaiqiang Li; Youmin Ying; Bingyu Chen; Ke Hao; Boxu Chen; Yu Zheng; Jianxin Lyu; Xiangming Tong; Xiaopan Chen; Ying Wang; Zhajun Zhan; Wei Zhang; Zhen Wang
Journal:  Oncotarget       Date:  2017-11-30

7.  Discovery of Polyoxypregnane Derivatives From Aspidopterys obcordata With Their Potential Antitumor Activity.

Authors:  Hong-Wei Guo; Yun-Gang Tian; Yi-Han Liu; Jia Huang; Jian-Xia Wang; Hua Long; Hua Wei
Journal:  Front Chem       Date:  2022-01-05       Impact factor: 5.221

8.  Comparative morpho-anatomical standardization and chemical profiling of root drugs for distinction of fourteen species of family Apocynaceae.

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  8 in total

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