Literature DB >> 15895556

HSP27 and cell death in spinocerebellar ataxia type 3.

Mingli Hsieh1, Hui-Fang Tsai, Wei-Hsiu Chang.   

Abstract

Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant spinocerebellar degeneration characterized by a wide range of clinical manifestations. In this review, we discuss the role(s) that heat shock protein 27 (HSP27) may play in the cell death process of spinocerebellar ataxia type 3.

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Year:  2005        PMID： 15895556     DOI： 10.1080/14734220410026248

Source DB:  PubMed          Journal:  Cerebellum        ISSN： 1473-4222            Impact factor:   3.847


  64 in total

1.  Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.

Authors:  F C Nucifora ; M Sasaki; M F Peters; H Huang; J K Cooper; M Yamada; H Takahashi; S Tsuji; J Troncoso; V L Dawson; T M Dawson; C A Ross
Journal:  Science       Date:  2001-03-23       Impact factor: 47.728

2.  Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.

Authors:  C J Cummings; Y Sun; P Opal; B Antalffy; R Mestril; H T Orr; W H Dillmann; H Y Zoghbi
Journal:  Hum Mol Genet       Date:  2001-07-01       Impact factor: 6.150

3.  Autosomal dominant cerebellar ataxia type I clinical features and MRI in families with SCA1, SCA2 and SCA3.

Authors:  K Bürk; M Abele; M Fetter; J Dichgans; M Skalej; F Laccone; O Didierjean; A Brice; T Klockgether
Journal:  Brain       Date:  1996-10       Impact factor: 13.501

4.  The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells.

Authors:  G Tezel; M B Wax
Journal:  J Neurosci       Date:  2000-05-15       Impact factor: 6.167

5.  Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation.

Authors:  T Rogalla; M Ehrnsperger; X Preville; A Kotlyarov; G Lutsch; C Ducasse; C Paul; M Wieske; A P Arrigo; J Buchner; M Gaestel
Journal:  J Biol Chem       Date:  1999-07-02       Impact factor: 5.157

6.  Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.

Authors:  D L Stenoien; C J Cummings; H P Adams; M G Mancini; K Patel; G N DeMartino; M Marcelli; N L Weigel; M A Mancini
Journal:  Hum Mol Genet       Date:  1999-05       Impact factor: 6.150

Review 7.  Glutamine repeats and neurodegeneration.

Authors:  H Y Zoghbi; H T Orr
Journal:  Annu Rev Neurosci       Date:  2000       Impact factor: 12.449

8.  Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation.

Authors:  M Ehrnsperger; S Gräber; M Gaestel; J Buchner
Journal:  EMBO J       Date:  1997-01-15       Impact factor: 11.598

9.  Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.

Authors:  N R Jana; M Tanaka; G h Wang; N Nukina
Journal:  Hum Mol Genet       Date:  2000-08-12       Impact factor: 6.150

10.  Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

Authors:  C J Cummings; M A Mancini; B Antalffy; D B DeFranco; H T Orr; H Y Zoghbi
Journal:  Nat Genet       Date:  1998-06       Impact factor: 38.330
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  4 in total

Review 1.  Modifiers and mechanisms of multi-system polyglutamine neurodegenerative disorders: lessons from fly models.

Authors:  Moushami Mallik; Subhash C Lakhotia
Journal:  J Genet       Date:  2010-12       Impact factor: 1.166

2.  RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients.

Authors:  Jörg-Christian Heinrich; Anne Tuukkanen; Michael Schroeder; Torsten Fahrig; Rudolf Fahrig
Journal:  J Cancer Res Clin Oncol       Date:  2011-07-22       Impact factor: 4.553

Review 3.  Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

Authors:  Serena Carra; Paola Rusmini; Valeria Crippa; Elisa Giorgetti; Alessandra Boncoraglio; Riccardo Cristofani; Maximillian Naujock; Melanie Meister; Melania Minoia; Harm H Kampinga; Angelo Poletti
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-03-25       Impact factor: 6.237

4.  Coenzyme Q10 Supplementation Increases Removal of the ATXN3 Polyglutamine Repeat, Reducing Cerebellar Degeneration and Improving Motor Dysfunction in Murine Spinocerebellar Ataxia Type 3.

Authors:  Yu-Ling Wu; Jui-Chih Chang; Hai-Lun Sun; Wen-Ling Cheng; Yu-Pei Yen; Yong-Shiou Lin; Yi-Chun Chao; Ko-Hung Liu; Ching-Shan Huang; Kai-Li Liu; Chin-San Liu
Journal:  Nutrients       Date:  2022-08-31       Impact factor: 6.706
  4 in total

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