Literature DB >> 15892800

The changing presentation of germ cell tumours of the testis between 1983 and 2002.

Thomas B Powles1, Jateesh Bhardwa, Johnathan Shamash, Sundhia Mandalia, Tim Oliver.   

Abstract

OBJECTIVE: To prospectively investigate the presentation of germ cell tumours (GCTs) of the testis in terms of stage or histology, as the incidence of this disease in increasing. PATIENTS AND METHODS: Patients diagnosed with GCT of the testis between 1983 and 2002 were categorised into three periods depending on the date of diagnosis of the GCT, and the presentational characteristics assessed. RESULTS There was a significant increase in the proportion of patients presenting with stage I disease (59% to 78%) and seminoma (43% to 58%) over this period. There was also a significant reduction in the size of the primary tumour (5 to 4 cm).
CONCLUSION: A greater proportion of patients with GCT are presenting with stage I seminoma, the reasons for which are unclear, although earlier diagnosis through improved awareness of GCT may be important.

Entities:  

Mesh:

Year:  2005        PMID: 15892800     DOI: 10.1111/j.1464-410X.2005.05504.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  15 in total

1.  Testosterone Level in Testicular Cancer Patients after Chemotherapy.

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Journal:  West Indian Med J       Date:  2016-04-29       Impact factor: 0.171

2.  Spontaneous metastasis in mouse models of testicular germ-cell tumours.

Authors:  J L Zechel; G T MacLennan; J D Heaney; J H Nadeau
Journal:  Int J Androl       Date:  2011-06-09

3.  Prognostic impact of LDH levels in patients with relapsed/refractory seminoma.

Authors:  Tom Powles; Caroline Bascoul-Mollevi; Andrew Kramar; Anja Lorch; Jörg Beyer
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Review 4.  Molecular Imaging for Evaluation of Viable Testicular Cancer Nodal Metastases.

Authors:  Gregory A Joice; Steven P Rowe; Michael A Gorin; Phillip M Pierorazio
Journal:  Curr Urol Rep       Date:  2018-11-09       Impact factor: 3.092

Review 5.  Contemporary management of early stage testicular seminoma.

Authors:  Ahmet Murat Aydin; Logan Zemp; Salim K Cheriyan; Wade J Sexton; Peter A S Johnstone
Journal:  Transl Androl Urol       Date:  2020-01

6.  Outcomes following retroperitoneal lymph node dissection in postchemotherapy residual masses in advanced testicular germ cell tumors.

Authors:  Prabhjot Singh; Siddharth Yadav; Sanjay Mahapatra; Amlesh Seth
Journal:  Indian J Urol       Date:  2016 Jan-Mar

7.  Testicular Germ-Cell Tumours: A Descriptive Analysis of Clinical Characteristics at First Presentation.

Authors:  Klaus-Peter Dieckmann; Hanna Richter-Simonsen; Magdalena Kulejewski; Raphael Ikogho; Henrik Zecha; Petra Anheuser; Uwe Pichlmeier; Hendrik Isbarn
Journal:  Urol Int       Date:  2018-04-12       Impact factor: 2.089

8.  Four Cycles of Etoposide plus Cisplatin for Patients with Good-Risk Advanced Germ Cell Tumors.

Authors:  Samuel A Funt; Deaglan J McHugh; Stephanie Tsai; Andrea Knezevic; Devon O'Donnell; Sujata Patil; Deborah Silber; Maria Bromberg; Maryann Carousso; Victor E Reuter; Brett S Carver; Joel Sheinfeld; Robert J Motzer; Dean F Bajorin; George J Bosl; Darren R Feldman
Journal:  Oncologist       Date:  2021-03-12

9.  Mortality and incidence of second cancers following treatment for testicular cancer.

Authors:  D Robinson; H Møller; A Horwich
Journal:  Br J Cancer       Date:  2007-01-30       Impact factor: 7.640

10.  Clinical outcome of robot-assisted residual mass resection in metastatic nonseminomatous germ cell tumor.

Authors:  J L H Ruud Bosch; Joost M Blok; Henk G van der Poel; J Martijn Kerst; Axel Bex; Oscar R Brouwer; Simon Horenblas; Richard P Meijer
Journal:  World J Urol       Date:  2020-09-21       Impact factor: 4.226

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