Literature DB >> 15890461

Cytotoxic activity of embelin from Lysimachia punctata.

Irma Podolak1, Agnieszka Galanty, Zbigniew Janeczko.   

Abstract

A major benzoquinone pigment, embelin (1), was isolated from the underground parts of Lysimachia punctata. Compound 1 showed a significant cytotoxic activity in vitro against B16 and XC cell lines with ED50 values of 13 microg/ml and 8 microg/ml, respectively.

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Year:  2005        PMID： 15890461     DOI： 10.1016/j.fitote.2005.02.006

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  6 in total

1.  Natural IAP inhibitor Embelin enhances therapeutic efficacy of ionizing radiation in prostate cancer.

Authors:  Yao Dai; Jeffrey Desano; Yang Qu; Wenhua Tang; Yang Meng; Theodore S Lawrence; Liang Xu
Journal:  Am J Cancer Res       Date:  2011       Impact factor: 6.166

2.  Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells.

Authors:  Rong Hu; Ke Zhu; Yingchun Li; Kun Yao; Rong Zhang; Huihan Wang; Wei Yang; Zhuogang Liu
Journal:  Med Oncol       Date:  2010-07-13       Impact factor: 3.064

3.  Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells.

Authors:  Da-Guang Wang; Ya-Bin Sun; Fei Ye; Wei Li; Punyaram Kharbuja; Ling Gao; David Y Zhang; Jian Suo
Journal:  Mol Cell Biochem       Date:  2013-10-18       Impact factor: 3.396

4.  Stress degradation studies on embelin.

Authors:  Galvina Ferreira; K S Laddha
Journal:  Indian J Pharm Sci       Date:  2013-03       Impact factor: 0.975

Review 5.  Plant Derived Phytocompound, Embelin in CNS Disorders: A Systematic Review.

Authors:  Uday P Kundap; Saatheeyavaane Bhuvanendran; Yatinesh Kumari; Iekhsan Othman; Mohd Farooq Shaikh
Journal:  Front Pharmacol       Date:  2017-02-27       Impact factor: 5.810

6.  XIAP inhibitor embelin induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells.

Authors:  You-Jin Lee; Bong-Soo Park; Hae-Ryoun Park; Su-Bin Yu; Hae-Mi Kang; In-Ryoung Kim
Journal:  Environ Toxicol       Date:  2017-07-19       Impact factor: 4.119
  6 in total

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