| Literature DB >> 15890332 |
Natalia Abramova1, Carol Charniga, Susan K Goderie, Sally Temple.
Abstract
Neural progenitor cells can be derived from a variety of developmental stages when they are preferentially proliferating, undergoing neurogenesis or undergoing gliogenesis. We used FACS sorting and the LeX surface marker to enrich neural progenitor cells from different embryonic stages and adult and compared their gene expression profiles using Affymetrix Microarrays. Our results show that, while there are common genes expressed in the progenitor cell population from all stages, there are also significant differences in gene expression patterns that correlate with stage-related behaviors. These data indicate that progenitor cells change during development and that adult and embryonic neural progenitor cells are intrinsically different.Entities:
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Year: 2005 PMID： 15890332 DOI： 10.1016/j.ydbio.2005.03.040
Source DB: PubMed Journal: Dev Biol ISSN： 0012-1606 Impact factor: 3.582