Literature DB >> 1588945

Free radicals in myocardial injury: experimental and clinical studies.

N K Ganguly1, K Nalini, S Wahi, V Dhawan, S Meenakshi, R N Chakravarti.   

Abstract

The exposure of cardiac cells to OFR generated artificially, showed a marked decrease (p less than 0.01) in cellular utilization of glucose along with a significant decrease in calcium uptake (p less than 0.05). We have also provided evidence for a direct relationship of neutrophil OFR production with the extent of myocardial ischemia in patients of myocardial infarction. Our data provides evidence for implication of OFR in myocardial injury and the pivotal role played by modulators like calcium, ECGF and prostaglandins in potentiating damage to the myocardium.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1588945     DOI： 10.1007/bf00229576

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  23 in total

Review 1.  The complexity of endothelial cells. A review.

Authors:  L F Fajardo
Journal:  Am J Clin Pathol       Date:  1989-08       Impact factor: 2.493

2.  Sodium-calcium ion exchange in cardiac membrane vesicles.

Authors:  J P Reeves; J L Sutko
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

3.  Influence of drugs that block calcium channels on the microbicidal function of human neutrophils.

Authors:  P H Kazanjian; J E Pennington
Journal:  J Infect Dis       Date:  1985-01       Impact factor: 5.226

4.  The independent effects of oxygen radical scavengers on canine infarct size. Reduction by superoxide dismutase but not catalase.

Authors:  S W Werns; M J Shea; E M Driscoll; C Cohen; G D Abrams; B Pitt; B R Lucchesi
Journal:  Circ Res       Date:  1985-06       Impact factor: 17.367

5.  Short-term therapy of atherosclerosis with low dose indomethacin: an experimental study.

Authors:  V Dhawan; N K Ganguly; S Majumdar; R N Chakravarti
Journal:  J Med Primatol       Date:  1990       Impact factor: 0.667

6.  Luminol-dependent chemiluminescence produced by neutrophils stimulated by immune complexes.

Authors:  K Cheung; A C Archibald; M F Robinson
Journal:  Aust J Exp Biol Med Sci       Date:  1984-08

7.  The pathophysiology of superoxide: roles in inflammation and ischemia.

Authors:  J M McCord; R S Roy
Journal:  Can J Physiol Pharmacol       Date:  1982-11       Impact factor: 2.273

8.  Multiple forms of endothelial cell growth factor. Rapid isolation and biological and chemical characterization.

Authors:  W H Burgess; T Mehlman; R Friesel; W V Johnson; T Maciag
Journal:  J Biol Chem       Date:  1985-09-25       Impact factor: 5.157

9.  Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

Authors:  J L Romson; B G Hook; S L Kunkel; G D Abrams; M A Schork; B R Lucchesi
Journal:  Circulation       Date:  1983-05       Impact factor: 29.690

10.  Effect of trimetazidine on membrane damage induced by oxygen free radicals in human red cells.

Authors:  I Maridonneau-Parini; C Harpey
Journal:  Br J Clin Pharmacol       Date:  1985-08       Impact factor: 4.335
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.