| Literature DB >> 15889176 |
Shengming Ma1, Shichao Yu, Zhihua Peng.
Abstract
In the presence of 5 mol% Sc(OTf)3, double indolylation of acetic acid 2-methylene-3-oxo-butyl ester with differently substituted indoles readily afforded beta,beta-bis(indolyl) ketones. The reaction may proceed via a Sc(OTf)3-catalyzed SN2'-type substitution and subsequent conjugate addition.Entities:
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Year: 2005 PMID： 15889176 DOI： 10.1039/b503378k
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876