| Literature DB >> 15888870 |
Robert L Levine1, Timothy C Allen, Joiner Cartwright, Philip T Cagle.
Abstract
A woman with a history of bilateral mastectomy and silicone implants for fibrocystic disease and a history of atrial septal defect repair presented with pleural nodules on a chest radiograph. A thorascopic biopsy performed for possible mesothelioma demonstrated chronic inflammation and focal pleural fibrosis due to a foreign-body reaction secondary to silicone. This was confirmed using scanning electron microscopy and energy-dispersive radiograph elemental analysis. As the population ages, the increasing frequency of ruptured silicone implants and the need for heart surgery may result in a corresponding increase in the risk for fibrothorax secondary to inadvertent silicone introduction during surgery.Entities:
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Year: 2005 PMID: 15888870 DOI: 10.1378/chest.127.5.1854
Source DB: PubMed Journal: Chest ISSN: 0012-3692 Impact factor: 9.410