Literature DB >> 15887951

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

David T Manallack1, Richard A Hughes, Philip E Thompson.   

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Year:  2005        PMID： 15887951     DOI： 10.1021/jm040217u

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  13 in total

Review 1.  Advances in targeting cyclic nucleotide phosphodiesterases.

Authors:  Donald H Maurice; Hengming Ke; Faiyaz Ahmad; Yousheng Wang; Jay Chung; Vincent C Manganiello
Journal:  Nat Rev Drug Discov       Date:  2014-04       Impact factor: 84.694

2.  Active site similarity between human and Plasmodium falciparum phosphodiesterases: considerations for antimalarial drug design.

Authors:  Brittany L Howard; Philip E Thompson; David T Manallack
Journal:  J Comput Aided Mol Des       Date:  2011-07-16       Impact factor: 3.686

3.  Structural findings of cinnolines as anti-schizophrenic PDE10A inhibitors through comparative chemometric modeling.

Authors:  Chanchal Mondal; Amit Kumar Halder; Nilanjan Adhikari; Tarun Jha
Journal:  Mol Divers       Date:  2014-05-01       Impact factor: 2.943

4.  A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice.

Authors:  Mar Cuadrado-Tejedor; Carolina Garcia-Barroso; Juan A Sánchez-Arias; Obdulia Rabal; Marta Pérez-González; Sara Mederos; Ana Ugarte; Rafael Franco; Victor Segura; Gertrudis Perea; Julen Oyarzabal; Ana Garcia-Osta
Journal:  Neuropsychopharmacology       Date:  2016-08-23       Impact factor: 7.853

5.  Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design.

Authors:  Michelle S Miller; Sweta Maheshwari; Fiona M McRobb; Kenneth W Kinzler; L Mario Amzel; Bert Vogelstein; Sandra B Gabelli
Journal:  Bioorg Med Chem       Date:  2017-01-16       Impact factor: 3.641

6.  Genome-wide transcriptional profiling of the cyclic AMP-dependent signaling pathway during morphogenic transitions of Candida albicans.

Authors:  Yong-Sun Bahn; Matthew Molenda; Janet F Staab; Courtney A Lyman; Laura J Gordon; Paula Sundstrom
Journal:  Eukaryot Cell       Date:  2007-10-19

7.  Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents.

Authors:  Ashraf H Abadi; Dalal A Abouel-Ella; Nermin S Ahmed; Bernard D Gary; Jose T Thaiparambil; Heather N Tinsley; Adam B Keeton; Gary A Piazza
Journal:  Arzneimittelforschung       Date:  2009

8.  Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.

Authors:  Matthew D Cullen; York-Fong Cheung; Miles D Houslay; Tracy L Hartman; Karen M Watson; Robert W Buckheit; Christophe Pannecouque; Erik De Clercq; Mark Cushman
Journal:  Bioorg Med Chem Lett       Date:  2007-12-14       Impact factor: 2.823

9.  Cyclic nucleotide specific phosphodiesterases of Leishmania major.

Authors:  Andrea Johner; Stefan Kunz; Markus Linder; Yasmin Shakur; Thomas Seebeck
Journal:  BMC Microbiol       Date:  2006-03-08       Impact factor: 3.605

10.  Physicochemical and Microbiological Stability of the Extemporaneous Sildenafil Citrate Oral Suspension.

Authors:  Attawadee Sae Yoon; Somchai Sawatdee; Chuthamas Woradechakul; Kridsada Sae Chee; Apichart Atipairin
Journal:  Sci Pharm       Date:  2015-07-07
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